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Bone mineral density is reduced by telmisartan in male spontaneously hypertensive rats.

CONCLUSION: Results showed that telmisartan negatively affected bones suggesting that caution should be taken in possible therapeutic applications for protecting bone health in hypertensive conditions. More studies are necessary to clarify the mechanisms through which telmisartan favors bone loss in this model. PMID: 27607362 [PubMed - as supplied by publisher]
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Tags: Pharmacol Rep Source Type: research

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Conclusions • Cyplexinol may effectively manage BMD loss experienced during osteoporosis, though more studies are warranted with larger samples to replicate these findings. Given that administration of Cyplexinol was found to improve density scores in both mild and severe cases, despite the extent of the patient's history of documented bone loss, Cyplexinol has a more diverse range of applicability than prescription medications, suggesting the first, natural alternative to bisphosphonates, hormone replacement therapies and antireceptor activator of nuclear factor kappa-B ligand (anti-RANKL) agents. Furthermore, due to...
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
Your Body Mass Index (BMI) is a measurement of your body fat percentage. And based on the results, you are labeled normal, overweight or obese.   But BMI can give you some crazy results. Using this measurement, I’m considered obese. And so is NFL superstar Tom Brady. You see, BMI only compares your height against your weight. It doesn’t distinguish between fat and muscle. But here’s the thing… Muscle is much denser than fat. So if you have a lot of muscle, you can have a high BMI but still be lean. There’s a much more reliable test to measure your body’s composition of fat and mu...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
CONCLUSIONS: Elevated FBG within the normal range is not associated with a significant loss of appendicular LM, but modifications in LM and FM trunk and total distribution with IFG suggest that nutritional and physical lifestyle strategies should be implemented in the pre-diabetic state. PMID: 29038669 [PubMed]
Source: Clin Med Res - Category: Research Authors: Tags: J Clin Med Res Source Type: research
The aim of this study was to describe femoral neck (FN) geometry among eumenorrheic underweight women around the age of peak bone mass. Proximal femur geometry and body composition were assessed in 12 underweight women and in 24 healthy controls using dual-energy X-ray absorptiometry. The Hip Structural Analysis program was used to determine bone geometry at the FN. The cross-sectional area (CSA) and the cross-sectional moment of inertia (CSMI) were significantly lower in underweight women than in controls (p  
Source: Journal of Clinical Densitometry - Category: Radiology Authors: Tags: Original Article Source Type: research
Introduction: Bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) is a fracture (Fx) risk and bone strength predictor. Patients with Fx have slightly decreased or normal DXA, therefore other factors such as the bone microarchitecture (MA) influence on the Fx risk. TBS (Trabecular Bone Score) is a texture measure derived of DXA lumbar image and provides information about MA predicting Fx risk. Aim: To evaluate TBS utility in postmenopausal women (PW) with probable osteoporosis. Methods: We evaluated 159 PW medical records.
Source: Bone - Category: Orthopaedics Authors: Tags: C ódigo: 41 Source Type: research
Abstract Background: Little is known about bone mineral density (BMD) during pregnancy. Advances in technology with lower radiation emissions by dual-energy X-ray absorptiometry instruments now permit the safe measurement of BMD during pregnancy.Objective: We evaluated maternal BMD during pregnancy as a function of vitamin D status in women of diverse racial/ethnic backgrounds.Design: A total of 301 women who underwent BMD measurements at 12-20 wk of gestation and again at 0-14 wk postpartum were included in this analysis. Women were a subset of subjects who were recruited for a randomized, controlled, double-blin...
Source: The American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Am J Clin Nutr Source Type: research
Authors: Peck B, Renzi T, Peach H, Gaultney J, Marino JS Abstract CONTEXT: Professional football linemen are at risk for sleep disordered breathing (SDB) compared to other types of athletes. It is currently unknown whether collegiate football linemen display a similar risk profile. OBJECTIVE: 1) Determine for the first time whether collegiate football linemen show risk for SDB, and 2) Test the hypothesis that SDB risk is higher in collegiate football linemen compared to an athletic comparison group. DESIGN: Descriptive laboratory study. SETTING: The Health Risk Assessment Laboratory. PARTICIPANTS: M...
Source: Journal of Sport Rehabilitation - Category: Sports Medicine Tags: J Sport Rehabil Source Type: research
ten L Abstract Background and purpose - The loss of bone mineral in the proximal femur following hip arthroplasty may increase the fracture risk around uncemented stems. We hypothesized that the surgical approach to the hip might influence bone mineral changes around the femoral stem in patients with a femoral neck fracture (FNF). Patients and methods - This was a pre-specified subgroup analysis (n = 51) of an ongoing randomized trial (n = 120) in patients with FNF. Participants were allocated to an uncemented hemiarthroplasty inserted through a direct lateral (Hardinge) approach or an anterolateral (modified Wats...
Source: Acta Orthopaedica - Category: Orthopaedics Authors: Tags: Acta Orthop Source Type: research
Abstract BackgroundSubclinical hyperthyroidism (SHyper) has been associated with increased risk of hip and other fractures, but the linking mechanisms remain unclear. ObjectiveTo investigate the association between subclinical thyroid dysfunction and bone loss. MethodsIndividual participant data analysis was performed after a systematic literature search in MEDLINE/EMBASE (1946–2016). Two reviewers independently screened and selected prospective cohorts providing baseline thyroid status and serial bone mineral density (BMD) measurements. We classified thyroid status as euthyroidism (thyroid‐stimulating hormone [TSH...
Source: Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Original Article Source Type: research
Abstract Evaluate the effect of the extract of Ginkgo biloba in the bone alkaline phosphatase, bone mineral density, in the mechanical properties of the tibia in rats with glucocorticoid-induced-osteoporosis. After osteoporosis induction, the rats were divided into five groups: Osteoporosis; EGb1 (28 mg/Kg); EGb2 (56 mg/Kg); alendronate (0.2 mg/animal) and control. The animals were treated during 20 and 30 days. The control group was compared with the osteoporosis's (Student's t-test), while the other were analyzed by ANOVA test followed by Tukey/Dunnett'T3 (p
Source: An Acad Bras Cienc - Category: Science Authors: Tags: An Acad Bras Cienc Source Type: research
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