In Vitro Activities of Tedizolid Compared with Other Antibiotics against Gram-positive Pathogens Associated with Hospital Acquired Pneumonia (HAP), Skin and Soft Tissue Infection (SSTI) and Bloodstream Infection (BSI) collected from Hospitals in China.

In Vitro Activities of Tedizolid Compared with Other Antibiotics against Gram-positive Pathogens Associated with Hospital Acquired Pneumonia (HAP), Skin and Soft Tissue Infection (SSTI) and Bloodstream Infection (BSI) collected from Hospitals in China. J Med Microbiol. 2016 Sep 2; Authors: Li S, Guo Y, Zhao C, Chen H, Hu B, Chu Y, Zhang Z, Hu Y, Liu Z, Du Y, Gui Q, Ji P, Zeng J, Cao B, Fu Q, Zhang R, Wang Z, Zhuo C, Feng X, Jia W, Jin Y, Xu X, Liao K, Ni Y, Yu Y, Xu X, Hu Z, Lei JE, Yang Q, Wang H Abstract To evaluate the in vitro antimicrobial activities of tedizolid, linezolid and other comparators against clinically significant Gram-positive cocci isolates from hospital-acquired pneumonia (HAP), skin and soft tissue infection (SSTI) and bloodstream infection (BSI), 2140 non-duplicate isolates (23.7% isolated from HAP, 46.8% from SSTI and 29.5% from BSI) were consecutively collected in 26 hospitals in 17 cities across China during 2014. These pathogens included 632 methicillin-resistant Staphylococcus aureus (MRSA), 867 methicillin-sensitive S. aureus (MSSA), 299 coagulase-negative Staphylococcus (CoNS), 104 Enterococcus faecalis, 99 E. faecium, 13 Streptococcus pneumoniae, 23 -hemolytic Streptococcus and 103 -hemolytic Streptococcus. Minimum inhibitory concentrations (MICs) of routine clinical antibiotics were determined by broth micro-dilution method according to Clinical and Laboratory Standards Institute (CLSI) guidelines 2015....
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research