From Chronic Kidney Disease To The Gift Of A New Life
Authors: Julika Wocial (JW) and Michael Moore (MM) MM The need for a donor After being diagnosed with chronic kidney disease I was able to lead a full and productive life for 25 years, although more recently my energy sagged. Looming options were dialysis, the 5-7 year wait for a deceased donor or a living donor. Dr Google said ihatedialysis.com. A living donor was the best option. But how? It must be different for each patient - a direct ask seemed weird, but silence was not an option. Happily I had made no secret of my lousy kidneys thus, 'How you doing?' lead on to the need. JW What it means to consider living donation I met Michael 18 years ago: my mentor and colleague. One day he told me his kidneys were failing; he needed a kidney transplant. After initial shock of the news and trying to figure out what it meant for him I started spending every free minute researching kidney diseases. A kidney transplant from a living donor was the best option - allowing Michael to live many more years. I asked myself - is there anything stopping me from being his donor? The surgery risks were minimal and I was willing to take them, the short and long-term consequences - four weeks out of work, four small scars, and lifting limitations for 3 months... All the literature out there, article after article, was proving that living donors live long and perfectly normal lives even 30 years after donation. The answer was simply NO... And shortly after, I told Michael I would like to be cons...
AbstractComplex Regional Pain Syndrome type 1 (CRPS-1) is a disabling painful disease whose hallmark is pain disproportionate to inciting event. CRPS is also characterized by symptoms and signs, such as vasomotor, sudomotor, trophic and motor changes. Therapeutic approach of CRPS-1 still remains a challenge for clinicians treating a disease with potential heavy consequences on patient prognosis. In the past years, the treatment with bisphosphonates (BPs) has gained some success as confirmed by the results of a number of meta-analyses. The aim of this paper is to point out the pivotal role of bone in CRPS pathogenesis. The ...
Rebecca Lane, now 39, from Sherborne, Dorset, weighed 18st 5lbs (116.5kg) when she was diagnosed in July 2016. She was forced to have her uterus and cervix removed.
Publication date: Available online 22 October 2018Source: Respiratory InvestigationAuthor(s): Naofumi ShinagawaAbstractBronchoscopy is one of the main techniques used for sampling lung tumor biopsies. In recent years, a large number of tumor specimens have been required to determine the best chemotherapy regimen for each patient; this personalized approach is known as precision medicine. In this review, radial endobronchial ultrasound; bronchoscopic navigation systems, including virtual bronchoscopic navigation and electromagnetic navigation; ultrathin bronchoscope,; and endobronchial ultrasound-guided transbronchial needl...
ConclusionProportion of SITC type 1 (persistent) in breast cancers on pre-treatment MRI as semi-automatically quantified using a CAD system is associated with absence of pathological complete response to neo-adjuvant chemotherapy with good specificity.
AbstractBackgroundPleural effusion at presentation in Hodgkin lymphoma has been associated with inferior outcome but has not been systematically evaluated.ObjectiveTo determine whether pleural effusion at presentation in children with Hodgkin lymphoma is a primary indicator of poor prognosis or secondary to associated factors.Materials and methodsChildren ’s Oncology Group (COG) AHOD0031, a randomized, response-based, centrally reviewed protocol, enrolled 1,712 eligible patients
CONCLUSIONS: These results suggest that long-term body weight gain after maturity in normal body weight participants may be associated with the incidence of CKD, independent of current body weight. PMID: 30344194 [PubMed - as supplied by publisher]
CONCLUSIONS: This cohort will reveal determinants of cardiometabolic risk factors and cancer risk factors during childhood. PMID: 30344192 [PubMed - as supplied by publisher]
Stereotactic ablative radiotherapy (SABR) can greatly increase how long oligometastatic...Read more on AuntMinnie.comRelated Reading: ASTRO: Weekly breast radiation therapy is safe ASTRO: AI's rad therapy future is in predicting outcomes Study gives all-clear for skin cream during radiation therapy PET/CT predicts success of rad therapy for spinal mets Is radiation therapy warranted for DCIS postlumpectomy?
This study shows that some genetic changes linked to cancer are present in surprisingly large numbers of normal cells. We still have a long way to go to fully understand the implications of these new findings, but as cancer researchers, we can't underestimate the importance of studying healthy tissue." Link: https://www.sanger.ac.uk/news/view/mutant-cells-colonise-our-tissues-over-our-lifetime
This study will enable us to know, with the highest level of scientific evidence, the number of sessions a patient should receive when starting the HD treatment, depending on his/her RRF. TRIAL REGISTRATION: Registered at the U.S. National Institutes of Health, ClinicalTrials.gov under the number NCT03239808. PMID: 30344012 [PubMed - as supplied by publisher]
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