Mango and the microbiota: Potential role of this superfruit in maintaining gut health
(Wild Hive) Research published in the Journal of Nutrition has for the first time, documented the potential effects of mango consumption on gut microbiota of mice. When samples were compared from the beginning to the end of the study period, mango supplementation was found to prevent the loss of beneficial gut bacteria often induced by a high-fat diet. This is an important finding as specific bacteria in the intestinal tract may play a role in obesity and obesity-related complications, such as type 2 diabetes.
A recentNew York Timesarticle reports that today ’s Democratic primary in Philadelphia partially represents a referendum on the city’s soda tax, even though it is not on the ballot. Incumbent Mayor Jim Kenney, the engineer of the 1.5 cents per ounce tax on sugary and artificially sweetened beverages which took effect in 2017, is facing two Dem ocratic challengers who both support repealing the controversial tax.Since its inception, the tax has faced vigorous opposition from a coalition of the beverage industry, grocery store owners, and Teamsters, as well as citizens and politicians who worried that it would un...
Conditions: Obesity; Type2 Diabetes; Bariatric Surgery Candidate Intervention: Procedure: Bariatric Surgery Sponsor: The Cleveland Clinic Enrolling by invitation
(Michigan Medicine - University of Michigan) A new discovery made mainly in mice could provide new options for getting the insulin-making 'factories' of the pancreas going again when diabetes and obesity have slowed them down. It could offer new pathways to ramping up insulin supply to get metabolism back on track in people with Type 1 and Type 2 diabetes, and obesity.
CONCLUSION: The implementation of the current training version cannot be recommended for medical rehabilitation. However, in consideration of relevant results a modification of the program could make sense. PMID: 31108553 [PubMed - as supplied by publisher]
ConclusionsFuture studies need to examine the true prevalence of OSA in a more representative sample of women with PCOS. Nevertheless, our results suggest that the prevalence of OSA in women with PCOS and obesity is high and clinicians should have a high index of suspicion of OSA in these women.
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-0879-2968Human fibroblast growth factor 21 (FGF21) is primarily produced and secreted by the liver as a hepatokine. This hormone circulates to its target tissues (e. g., brain, adipose tissue), which requires two components, one of the preferred FGF receptor isoforms (FGFR1c and FGFR3c) and the co-factor beta-Klotho (KLB) to trigger downstream signaling pathways. Although targeting FGF21 signaling in humans by analogues and receptor agonists results in beneficial effects, e. g., improvements in plasma lipids and decreased body weight, it failed to recapitulate the i...
To secure adequate carbohydrate supply in pregnancy, the Institute of Medicine (IOM) recommends a minimum amount of carbohydrates of 175 g daily. Currently a low carbohydrate diet is a popular health trend in the general population and this might also be common among overweight and obese pregnant women with type 2 diabetes (T2D). Thus, we explored carbohydrate consumption among pregnant women with T2D including women with type 1 diabetes (T1D) for comparison.
Publication date: Available online 18 May 2019Source: PeptidesAuthor(s): Allison B. Reiss, Daniel S. Glass, Eric Lam, Amy D. Glass, Joshua De Leon, Lora J. KasselmanAbstractCardiovascular disease (CVD) remains the leading cause of death worldwide, despite multiple treatment options. In addition to elevated lipid levels, oxidative stress and inflammation are key factors driving atherogenesis and CVD. New strategies are required to mitigate risk and most urgently for statin-intolerant patients. The neuropeptide hormone oxytocin, synthesized in the brain hypothalamus, is worthy of consideration as a CVD ancillary treatment be...
ConclusionsWe were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances.
ConclusionsMetformin may exhibit anti ‐inflammatory effects in macrophages via the induction of Dicer and the subsequent upregulation of miR‐34a‐5p and miR‐125b‐5p.This article is protected by copyright. All rights reserved.