Antibacterial and antifungal activity of Salvia apiana against clinically important microorganisms.

This study evaluated the antibacterial and anticandidal effects of a hexane extract from the root of Salvia apiana. Salvia extracts at concentrations of 27, 13.5, 6.8 and 3.4mg/ml caused growth inhibition of Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis and Candida albicans. However, no significant effect was observed on Escherichia coli and Candida tropicalis in comparison to vehicle. It was here demonstrated for the first time that Salvia apiana has an important antimicrobial effect on human pathogens of great clinical value, thus opening the field to continue the evaluation of this lamiaceous plant for its future use as a therapeutic agent. PMID: 27595508 [PubMed - as supplied by publisher]
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research

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Synthesis, in vitro biological evaluation and in silico molecular docking studies of novel β-lactam-anthraquinone hybrids. Bioorg Chem. 2019 Dec 17;95:103515 Authors: Mohamadzadeh M, Zarei M, Vessal M Abstract Schiff bases from 2-aminoanthraquinone have been prepared by reaction with aldehydes and used to prepare novel β-lactam-anthraquinone hybrids via [2+2] ketene-imine cycloaddition (Staudinger reaction) reaction. In vitro antibacterial studies of all synthesized compound were carried out against three gram-positive strains Staphylococcus aureus (Methicillin-resistant strain), Enterococcu...
Source: Bioorganic Chemistry - Category: Chemistry Authors: Tags: Bioorg Chem Source Type: research
This study is the first report revealing cytotoxic, antimicrobial and nitric oxide inhibitory activity of supercritical carbon dioxide extract of Prunus persica leaves. PMID: 31686285 [PubMed - as supplied by publisher]
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
Publication date: 1 February 2020Source: Materials Chemistry and Physics, Volume 241Author(s): Irina Zarafu, Ali Abed Jebur Al Taweel, Carmen Limban, Marcela Popa, Luminița Măruțescu, Mariana Carmen Chifiriuc, Gratiela Gradisteanu Pircalabioru, Daniela Culiță, Corneliu Ghica, Petre IonitaAbstractAminopropyl-silica nanoparticles S0 were obtained and further functionalized with eight halogen-reactive organic compounds 1–8, leading to the S1–S8 hybrid organic-inorganic materials, with spherical morphology and having a 50–200 nm size, as showed TEM analysis. These were further characterized by IR and D...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Publication date: Available online 25 October 2019Source: Journal of Molecular StructureAuthor(s): Ömer Yurdakul, Dursun Ali Köse, Onur Şahin, Gülçin Alp AvcıAbstractTwo new tetrahedral acesulfame complexes, acesulfamato(N)acesulfamato(O)bis(3-aminopyridine) zinc(II) (C18H20N6O8S2Zn, Zn-ace-3ap) and bis(acesulfamato-O)bis(benzotriazole)zinc(II) (C20H18N8O8S2Zn, Zn-ace-bta), were synthesized and characterized by single crystal X-ray diffraction, FT-IR spectroscopy, elemental analysis and thermal analysis techniques(TGA, DTA, DTG). The first compound, Zn-ace-3ap, crystallizes in triclinic space group ...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 24 September 2019Source: Journal of Molecular StructureAuthor(s): Romana Machníková, Lucie Janovská, Lucie BrulíkováAbstractHerein, we report the polymer-supported synthesis of new pyrimidine derivatives and their antimycobacterial and antimicrobial activity. Our methodology is based on the fast and efficient solid-phase synthesis having the ability to implement structural diversity from the readily available building blocks through minimum synthetic route and with high yields. Our method was validated in the synthesis of a model chemical library prepare...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
ni IB Abstract The essential oils (EOs) obtained from the leaves of Iryanthera polyneura Ducke trees was chemically assessed and tested for the ability of inhibit the growth of Candida albicans, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans and S. sanguis. The oil was also tested against breast (MCF-7) and prostate (PC-3) cancer cell lines. Minimum bactericidal concentrations (MBCs) and inhibitory concentrations 50 (IC50) values were obtained. EOs were active against Gram positive bacteria. Spathulenol, α-cadinol and τ-muurolol were major com...
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Tags: Chem Biodivers Source Type: research
CONCLUSIONS: The use of orthodontic appliances alters the status of the oral cavity; it has impact on the colonization of oral biofilm by opportunistic/pathogenic strains, and increases the risk of their dissemination to various human tissues and organs. Pretreatment examination of oral microbiome, its monitoring particularly during treatment with fixed appliances, and preventive elimination of the potentially pathogenic strains to avoid health complications, are highly recommended, especially in patients with impaired immunity. PMID: 31232051 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - Category: Environmental Health Authors: Tags: Ann Agric Environ Med Source Type: research
We reported the fabrication of bismuth-doped copper aluminate nanocomposites (BiCuAl2O4 NCs) via microwave-assisted method for antioxidant and antibacterial performances. As-fabricated material was characterized by electron spectroscopy techniques like X-ray diffraction (XRD), Fourier transform infrared (FTIR), energy dispersive spectroscopy (EDS), diffuse reflectance spectroscopy (DRS), X-ray photoelectron spectroscopy (XPS), Raman, scanning electron microscopy (SEM) and BET. The structural and chemical state authentication of material was confirmed by XRD, FTIR, EDS, Raman and XPS, while morphology explored by SEM. The s...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Ramiro Ríos-Gómez María Isabel Aguilar Verbena carolina L. (Verbenaceae) is used as a decoction in Mexican folk medicine with applications against digestive problems and for dermatological infections. The present work firstly reported HPLC analysis, as well as the free radical scavenging capacity of the extracts and isolated compounds. Antimicrobial analyses of these substances against the bacteria Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Salmonella typhi and the fungi Candida albicans, Trichophyton mentagrophytes and T. rubrum were also tested, as well as the acute or...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
In conclusion, potential biological applications of PF-SeNPs were explored by antibacterial, antifungal, antioxidant and biocompatibility assays. Materials and Methods Chemicals and Reagents Sodium selenite (98%), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT), Tween 80, methanol, acetate buffer, tetracycline, nystatin, rhodamine 123, caspase-3 kit, Dulbecco’s modified Eagle media (DMEM), Folin-Ciocalteu reagent, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), Dulbecco’s phosphate buffered saline pH 7.4 (DPBS) and fetal bovine serum (FBS) w...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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