Devon Walker Foundation hosts celebrity basketball game to help people with spinal cord injuries

Former Tulane University football player Devon Walker broke his neck during a football game in Tulsa, Oklahoma, in September of 2012 and was paralyzed from the neck down.
Source: - Health - Category: Consumer Health News Source Type: news

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CONCLUSIONS: The above findings suggested that PYC can improve motor function and reduce neuronal apoptosis after SCI by stabilizing the MMP through the inhibition of oxidative stress. ABBREVIATIONS: DMSO: dimethyl sulfoxide; IHC: immunological histological chemistry; MDA: malondialdehyde; PBS: phosphate buffered saline; PMSF: phenylmethanesulfonyl fluoride; PVDF: polyvinylidene difluoride; PYC: Pycnogenol; RIPA: radio immunoprecipitation assay; SCI: spinal cord injury; SOD: superoxide dismutase. PMID: 32497471 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
In this study, we summarized clinical differences between acute attack myelitis of NMOSDs and ITM, we further screened serum auto-antibodies to help understand the two distinct clinical entities. METHODS: This is a retrospective study on 48 NMOSD patients and 49 ITM patients in neurological department of Nanjing Drum Tower Hospital from 2013 to 2019. Clinical, CSF and MRI profiles on the acute episode were also compared between NMOSD patients and ITM patients. Serum AQP4 and auto-antibodies were tested. Clinical parameters were further compared between NMOSD patients with and without auto-antibodies. RESULTS: Compa...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Authors: Kim SJ, Cho YS, Park JM, Na YG, Kim KH Abstract Neurogenic bladder (NB) after spinal cord injury (SCI) is a common complication that inhibits normal daily activities and reduces the quality of life. Regrettably, the current therapeutic methods for NB are inadequate. Therefore, numerous studies have been conducted to develop new treatments for NB associated with SCI. Moreover, a myriad of preclinical and clinical trials on the effects and safety of stem cell therapy in patients with SCI have been performed, and several studies have demonstrated improvements in urodynamic parameters, as well as in sensory an...
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
Publication date: Available online 3 June 2020Source: Physiology &BehaviorAuthor(s): Fatemeh Ramezani, Maryam Razmgir, Kiarash Tanha, Farinaz Nasirinezhad, Ali Neshasteriz, Amir Bahrami-Ahmadi, Michael R Hamblin, Atousa Janzadeh
Source: Physiology and Behavior - Category: Physiology Source Type: research
AbstractPurpose of ReviewThe topics to be discussed in this article include bone loss in the regions of the lower extremity that are most prone to fracture, the risk factors for fracture, the diagnosis of osteoporosis in persons with spinal cord (SCI), the determination of the fracture threshold at the knee, and a brief discussion of future directions.Recent FindingsExtensive cross-sectional studies, but a paucity of longitudinal studies, that describe the precipitous bone loss occurs during the acute phase of SCI that likely continues, albeit more gradually, over the lifetime. The distal femur (DF) and proximal tibia (PT)...
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research
Spinal cord injury (SCI) is a clinical tough neurological problem without efficient cure currently. Blood-spinal cord barrier (BSCB) interruption is not only a crucial pathological feature for SCI process but is a possible target for future SCI treatments; however, few treatments have been developed to intervene BSCB. In the present study, we intravenously injected CO-releasing molecule3 (CORM-3), a classical exogenous CO donor, to the rats experiencing SCI and assessed its protection on BSCB integrity in rats. Our results demonstrated that the exogenous increasing of CO by CORM-3 blocked the tight junction (TJ) protein de...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Source: Expert Opinion on Biological Therapy - Category: Drugs & Pharmacology Authors: Source Type: research
The therapeutic effects of adipose-derived mesenchymal stem cell (ADSC) transplantation have been demonstrated in several models of central nervous system (CNS) injury and are thought to involve the modulation...
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Research Source Type: research
Cognitive dysfunction (CD) is pervasive in individuals who have chronic spinal cord injuries (SCI). Although classically associated with concomitant traumatic brain injuries, many other causes have been proposed, including premorbid neuropsychological conditions, mood disorders, substance abuse, polypharmacy, chronic pain and fatigue, sleep apnea, autonomic dysregulation, post-intensive care unit syndrome, cortical reorganizations, and neuroinflammation. The consequences of CD are likely widespread, affecting rehabilitation and function. CD in those with SCI should be recognized, and potentially treated, in order to provid...
Source: Physical Medicine and Rehabilitation Clinics of North America - Category: Rehabilitation Authors: Source Type: research
This article details the ISNCSCI update from 2015 and revision in 2019.
Source: Physical Medicine and Rehabilitation Clinics of North America - Category: Rehabilitation Authors: Source Type: research
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