Speckle Tracking Echocardiographic Imaging in Metabolic Cardiomyopathies

AbstractPurpose of ReviewThe aging population in western nations has experienced an increase in the prevalence of heart failure alongside the increasing rates of obesity, metabolic syndrome, and type 2 diabetes mellitus. Clinical studies have established a strong link between these metabolic derangements and the risk of heart failure.Recent FindingsEchocardiography is an essential tool in supporting the diagnosis of heart failure and establishing its phenotype. Advanced echocardiographic methods based on speckle tracking echocardiography provide unique insights into myocardial mechanics and underlie the novel approach to phenotype classification of heart failure patients.SummaryThe current review summarizes the myocardial mechanics assessment based on speckle tracking echocardiography focusing on diabetic cardiomyopathy. It highlights potential applications and promises of this approach.
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research

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Abstract Cardiovascular disease is recognized as a leading cause of death worldwide, but the risk of death is 2-3 times higher for individuals with diabetes. NLRP3 inflammasome activation is a leading pathway of vascular damage, and new treatment methods are needed to reduce NLRP3 inflammasome expression, along with a detailed understanding of how those treatments work. In a series of assays on human vascular endothelial cells that were exposed to high concentrations of free fatty acids (FFA) to induce a diabetes-like environment, we found a significant impact of cilostazol, a vasodilator widely used to treat bloo...
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Artif Cells Nanomed Biotechnol Source Type: research
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Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
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Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
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Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
ConclusionNSM and SSM patients have similar reoperation rates and LOS; however, complication rate is higher in NSM patients.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
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Source: Journal of Experimental Social Psychology - Category: Psychiatry & Psychology Source Type: research
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Source: Frontiers in Physiology - Category: Physiology Source Type: research
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Source: Frontiers in Physiology - Category: Physiology Source Type: research
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Source: Frontiers in Physiology - Category: Physiology Source Type: research
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