Weight Loss Pills And Products Don't Work And Aren't Safe

Our ancestors lived in a feast or famine world. When you don't know where your next meal is coming from, or when it will arrive, the smart play is to pig out every time food is available. Our genes are programmed to extract as much energy as possible from what we eat and to store any extra energy in fat reservoirs, available in reserve for future famines. These deeply ingrained genetic tendencies worked great in the austere world of our ancestors, but are a disaster in our current world of refrigerators, ubiquitous fast food joints and milk shakes. Only one third of Americans are now able to maintain a normal weight; one third are overweight; and one third are obese. Excess weight is a risk factor for most illnesses, and for many people is also a consuming cosmetic concern. Pharma knows that a safe and effective diet pill would be one of its biggest potential cash cows. Over the past 80 years, drug companies have done extensive research and have developed many products trying to capture the enormous market of unsuccessful weight watchers. None have worked well; all have had considerable risks. But hope and hype always spring eternal. Dick Bijl is the perfect person to describe this troubling story and provide much needed cautions against our future credulity. He is president of the International Society of Drug Bulletins, representing 53 national drug bulletins, each engaged in evaluating the pluses and minuses of medications. Drug bulletins are essential-truthful antidote...
Source: Science - The Huffington Post - Category: Science Source Type: news

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CONCLUSION: In hypertensive and diabetic patients, higher OPG values were associated with impaired LA function assessed by 2D-STE. In this high-risk patient group, serum OPG can be used as a risk predictor for LA mechanical dysfunction. PMID: 32462219 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Publication date: Available online 29 May 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Khushdeep Bandesh, Dwaipayan Bharadwaj
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - Category: Biochemistry Source Type: research
Effect of unsymmetrical oligo-phenylene-ethynylene OPE3 against multidrug-resistant bacteria in vitro and in vivo. J Chemother. 2020 May 28;:1-9 Authors: Yuan Q, Wang Y, Yao P, Lv J, Wang Q, Sun F, Feng W Abstract The rapid proliferation of multidrug-resistant (MDR) bacterial infections has posed the serious health threats. Photodynamic therapy is considered one of the most promising therapeutic strategies for combating bacterial resistance. In the present study, we synthesized an unsymmetrical oligo-p-phenylene ethynylene (OPE), namely OPE3, and investigated its antimicrobial activity agains...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
Authors: Bilkhu R, Billè A Abstract The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID-19 undergoing treatment is mandatory. We reviewed the experience of the National Institute of Cancer in Milan and compared it with our experience. PMID: 32462984 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
Conclusion: Adding a BM-TT to FIT-screening considerably reduces colonoscopy burden, but could also decrease screening effectiveness. Combining FIT15 with a high polyp sensitivity BM-TT seems most promising. PMID: 32462913 [PubMed - as supplied by publisher]
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractThis video shows the case of a 64-year-old morbidly obese woman, with a non-adjustable gastric band, who consulted for weight regain and gastroesophageal reflux disease (GERD) symptoms and was converted to Roux-en-Y gastric bypass (RYGB). The operative technique included extensive lysis of adhesions, complete band dissection, partial gastrectomy of the fundus and body due to band erosion and conversion to RYGB.
Source: Obesity Surgery - Category: Surgery Source Type: research
Source: Obesity Surgery - Category: Surgery Source Type: research
The review was not registered for systematic reviews and meta-analyses, and should be disregarded.
Source: Obesity Surgery - Category: Surgery Source Type: research
Source: Obesity Surgery - Category: Surgery Source Type: research
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