Hemosiderotic synovitis: Highlighting the role of T2 ∗ weighted sequence in skeletal MRI

We report a rare case of spontaneous hemosiderotic synovitis of knee joint in an otherwise healthy young male player, with no associated findings of bleeding disorder, inflammatory arthritis or other systemic illness. The role of T2 weighted gradient recalled echo (GRE) (T2∗WI) MRI sequence in skeletal imaging sticks out from this report. Close differential diagnosis of pigmented villonodular synovitis (a benign neoplastic condition) should be excluded by histological examination. Treatment aimed to prevent articular degeneration by prompt intervention.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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CONCLUSION: We hypothesize that the whole-body cryotherapy was responsible for this stroke. PMID: 32994067 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
HORSHAM, PA, September 30, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved SIMPONI ARIA® (golimumab) for patients 2 years of age and older for the treatment of active pJIA and has extended the PsA indication for this same patient population. “This latest FDA approval of SIMPONI ARIA for pediatric use in active pJIA and active PsA not only brings a new option to young patients living with these diseases but also adds to the growing body of evidence for this treatment,” said Mathai Mammen, M.D., Ph.D., Glob...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
Conclusions: Occipital plate fixation was successful for pediatric cervical spine fusion in this diverse cohort. The only procedure-related complication demonstrated was delayed union or nonunion and implant loosening (4/34, 12%) and there were no plate-related complications. This novel case series shows that occipital plate fixation is safe and effective for pediatric patients with complex diagnoses. Level of Evidence: Level IV—case series.
Source: Journal of Pediatric Orthopaedics - Category: Orthopaedics Tags: Spine Source Type: research
Conclusions: This study has demonstrated collective CX3CL1/CX3CR1 axis involvement in hemophilic arthropathy pathogenesis introducing new interesting diagnostics and a therapeutic target. PMID: 32884948 [PubMed - in process]
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Conclusion: Administration of Orthoboon, i.e., GS, with a combination of Vitamin C and collagen was proved to be of a significant benefit in the test group than in the control group.
Source: Journal of Indian Society of Periodontology - Category: Dentistry Authors: Source Type: research
A 66-year-old male patient with psoriatic arthritis who received methotrexate (MTX) 25 mg/wk was hospitalized for ureteral reimplantation, presenting nausea, vomiting, loss of appetite, and oral ulceration. Physical examination revealed multiple ulcerations in the lower labial mucosa, with intense painful symptoms and spontaneous bleeding. The diagnostic hypothesis was of ulcerations associated with the drug. Treatment was performed with 0.05% clobetasol propionate with no satisfactory response.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: 20190684 Source Type: research
Conclusion: Administration of Orthoboon, i.e., GS, with a combination of Vitamin C and collagen was proved to be of a significant benefit in the test group than in the control group.
Source: Journal of Indian Society of Periodontology - Category: Dentistry Authors: Source Type: research
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review. Am Fam Physician. 2020 Aug 15;102(4):229-233 Authors: Reamy BV, Servey JT, Williams PM Abstract Henoch-Schönlein purpura, now called immunoglobulin A (IgA) vasculitis, is a systemic, immune complex-mediated, small-vessel leukocytoclastic vasculitis characterized by nonthrombocytopenic palpable purpura, arthritis, and abdominal pain. It is the most common vasculitis in children but can also occur in adults. Diagnostic testing is required only to exclude other etiologies of purpura, to identify renal involvement, and, if indicat...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
In conclusion, comorbid PSVD might be a cause of portal hypertension in FS patients. The present case had excellent outcome in two years, which supported the use of endoscopic therapy for the management of variceal bleeding in FS patients. Further large prospective study is needed to confirm the findings. PMID: 32714976 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Among the many remarkable things that have happened since the COVID-19 pandemic began is that a lot of our usual medical care has simply stopped. According to a recent study, routine testing for cervical cancer, cholesterol, and blood sugar is down nearly 70% across the country. Elective surgeries, routine physical examinations, and other screening tests have been canceled or rescheduled so that people can stay at home, avoid being around others who might be sick, and avoid unknowingly spreading the virus. Many clinics, hospitals, and doctors’ offices have been closed for weeks except for emergencies. Even if these f...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Health care Healthy Aging Men's Health Women's Health Source Type: blogs
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