Angiotensin converting-enzyme inhibition restores glomerular glycosaminoglycans in rat puromycin nephrosis.

CONCLUSION: Treatment with ACEI improves permselectivity properties of the glomerular capillary wall by maintaining its GAG content. This finding provides an additional new mechanism, whereby ACEI exert anti-proteinuric effects.
PMID: 27591087 [PubMed - as supplied by publisher]

Source: Experimental and Toxicologic Pathology - August 29, 2016 Category: Pathology Authors: Herman-Edelstein M, Chagnac A, Nevo Z, Skutelsky E, Evron Y, Hirsch Y, Ben-Dor L, Schwartz I, Schwartz D, Weinstein T Tags: Exp Toxicol Pathol Source Type: research