Central Odontogenic Fibroma of the Mandible
Condition: Fibromatosis Intervention: Drug: Triamcinolone Acetonide Sponsor: Mayo Clinic Recruiting
We report a highly unusual case of cemento-osseous dysplasia in a 32-year-old male complaining of discomfort of the left cheek. The radiographic examination revealed that a spherical radiopaque lesion, which involved a tooth, was located in the left maxillary sinus. A definitive diagnosis could not be made based only on the radiographic and clinical findings. An excisional biopsy was performed by opening the left maxillary sinus under the general anaesthesia. Histopathological examination revealed that the lesion consists of fibrous tissue, woven bone and masses of cementum-like material associated with a dislocated tooth....
ConclusionsOur paper highlights that patients with COF who present a lesion located in the maxilla with multilocular aspects and cortical bone perforation tend to show a higher recurrence rate.
We report a 5-year-old male child with recurrent benign OF of the orbit. The child had two episodes of recurrence in a span of 18 months. Computed tomography (CT) of orbit showed a large, lobulated expansile fibro-osseous lesion involving the greater wing of sphenoid and orbital roof without intracranial extension. An excisional biopsy was done though an orbital approach. Histopathology showed fibroblast rich stroma with bony trabeculae. Osteoblastic rimming without any mitotic activity was suggestive of juvenile OF. The child developed a recurrence 6 months following the initial excision, and surgical excision w...
To integrate the available data published on central odontogenic fibroma (COF) into a comprehensive analysis of its clinical/radiologic/histological features.
Polyfibromatosis is a rare syndrome in which patients may develop spontaneous keloid formation in association with penile, palmar, or plantar fibromatoses. Rare and aggressive forms of polyfibromatosis have been reported to cause erosive arthropathy. Here, we describe the case of a young man with spontaneous keloid formation and aggressive fibromatoses with erosive arthropathy resulting in amputation. A 23-year-old Caucasian man presented to our clinic with a history of multiple spontaneous keloids, contractures and nodules of the hands, and bilateral foot pain.
Lipoblastoma is a rare benign mesenchymal tumor of infancy and childhood. The most common presentation is a painless subcutaneous soft tissue mass, but there are other unique clinical presentations that are important to recognize. The differential is broad and includes sarcoma, vascular tumor, myofibroma, and other fibromatoses. It is most often encountered on the trunk and extremities of children and symptoms vary depending on localization. Occasionally children present with compression of adjacent organs by a lipoblastoma.
Background: Acrochordons are a one of the commonest type of benign cutaneous tumors. These are soft skin fibromas, and have been thought to represent as a cutaneous marker of metabolic syndrome. Treatments like snipping, cryotherapy, electrocautery, and radiofrequency ablation though effective, have there own limitations.
Two female chinchillas were presented with reduced appetite and production of small fecal pellets. Physical examination of both chinchillas revealed a reduced vaginal membrane, bloody vaginal discharge, and a palpable mass in the caudal abdomen. Radiographic images revealed soft tissue masses in the caudal abdomen of both animals. In addition, the first case was examined by ultrasound, which identified two cystic masses, both originating from one of the uteri. Both chinchillas were euthanized due to progressive clinical deterioration with both animals undergoing postmortem examinations.