Central Odontogenic Fibroma of the Mandible

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Tags: Case Reports Source Type: research

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This article reports the case of a 29-year-old woman who presented with a painless, reddish mass in the right vestibular mandibular gingiva between the second premolar and the first molar. Radiographic examination revealed small crestal bone loss in the region. Microscopic analysis revealed a tumor composed of cellular fibroblastic connective tissue intermingled with conspicuous islands and strands of apparently inactive odontogenic epithelium. The final diagnosis was POF. No clinical signs of recurrence were observed 22 months after surgical excision. POF may be clinically mistaken for other common gingival lesions, such ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
Desmoid-type fibromatosis (DTF) is a rare, soft tissue tumor of mesenchymal origin which is characterized by local infiltrative growth behavior. Besides “wait and see”, surgery and radiotherapy, several systemic treatments are available for symptomatic patients. Recently, targeted therapies are being explored in DTF. Unfortunately, effective treatment is still hampered by the limited knowledge of the molecular mechanisms that prompt DTF tumorigenesis. Many studies focus on Wnt/β-catenin signaling, since the vast majority of DTF tumors harbors a mutation in the CTNNB1 gene or the APC gene. The establishe...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
The objective of this study was to investigate, comparatively, the immunohistochemical expression of major non-collagenous proteins (osteonectin [ON], osteopontin [OP], bone sialoprotein [BSP] and osteocalcin [OC]) of mineralized tissue extracellular matrix in 22 cases of fibrous dysplasias, 16 of cemento-ossifying fibromas and 16 of cemento-osseous dysplasias. ON maintained the same expression profile in all cases; the staining for OP was negative in fusiform cells producing cementoid globules and weak, as well as heterogeneous, in high mineralized matrixes; there was negativity for BSP in cementoid globules and in the fu...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Objectives: The aim of this study was to compare the time from diagnostic and resection, with or without treatment, in submucosal fibroma, till complete removal.
Source: Maturitas - Category: Primary Care Authors: Tags: P108 Source Type: research
AbstractUterine fibromatosis is common in women, with an estimated prevalence of up to 15 –50% after 35 years. About 80% of women affected by fibromatosis have symptoms and require medical or surgical treatment. Nowadays, the gold standard for the surgical treatment of uterine fibromatosis is the use of minimally invasive surgery. The surgical skills and improvements offered by roboti c approach can be relevant in reproductive surgery, in particular in minimally invasive myomectomy. However, the lack of tactile feedback of robotic platform is an important technical drawback that can reduce the accuracy of surgic...
Source: Journal of Robotic Surgery - Category: Surgery Source Type: research
Publication date: May 2019Source: Journal of the American College of Radiology, Volume 16, Issue 5, SupplementAuthor(s): Expert Panel on Women’s Imaging:, Mostafa Atri, Abdullah Alabousi, Caroline Reinhold, Esma A. Akin, Carol B. Benson, Priyadarshani R. Bhosale, Stella K. Kang, Yulia Lakhman, Refky Nicola, Pari V. Pandharipande, Maitray D. Patel, Gloria M. Salazar, Thomas D. Shipp, Lynn Simpson, Betsy L. Sussman, Jennifer W. Uyeda, Darci J. Wall, Bradford P. Whitcomb, Carolyn M. Zelop, Phyllis GlancAbstractThere are approximately 9.1 pelvic surgeries performed for every histologically confirmed adnexal malignancy in...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
Desmoid-type fibromatosis (DTF) is a lesion characterized by clonal proliferation of myofibroblasts, which exhibits an infiltrative growth pattern. It is necessary for them to be distinguished from other fibro...
Source: Diagnostic Pathology - Category: Pathology Authors: Tags: Research Source Type: research
We present a 13-year-old girl who had been operated for the intraspinal mass in upper thoracic spine and paraparesis with thoracic limited laminectomy and excision of the tumor mass elsewhere. The histopathological examination was reported to be aggressive fibromatosis. After 2 years, she presented again with 1-year duration of progressive deformity in the upper thoracic spine and weakness of both lower limbs. Focal kyphosis at T4-T5 was measuring 68°. Magnetic resonance imaging (MRI) showed recurrent tumor involvement of posterior elements of T2-T5 and paravertebral soft tissues with signal changes in the cord at T2-T...
Source: Journal of Orthopaedic Surgery - Category: Orthopaedics Authors: Tags: J Orthop Surg (Hong Kong) Source Type: research
This study was approved by and carried out in accordance with the recommendations of the Bioethical Committee of the Jagiellonian University in Kraków, Poland (permit numbers 122.6120.337.2016 and KBET/310/B/2012). All subjects gave written informed consent in accordance with the Declaration of Helsinki. Clinical characteristics of patients included in the study are shown in Supplementary Table 1. The epithelial layer was separated enzymatically by treatment with dispase at 4°C overnight (o/n) and subjected to three rounds of digestion with trypsin (BioWest) for 10 min at 37°C. After centrifugation, the obt...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Authors: Bagga R, Garg S, Muthyala T, Kalra J, Kumar Saha P, Arora A, Singla R, Singh T, Gupta N PMID: 31020883 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
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