Two new lupane saponins from Schefflera kwangsiensis

Publication date: December 2016 Source:Phytochemistry Letters, Volume 18 Author(s): Yan Wang, Chun-Lei Zhang, Yan-Fei Liu, Ruo-Yun Chen, Feng-Zhong Wang, De-Quan Yu Two new lupane saponins, Schekwanglupasides A and B (1 and 2), together with three esters (3–5) of known lupane saponins were isolated from the aerial parts of Schefflera kwangsiensis. The structures of these compounds were elucidated on the basis of spectroscopic data analysis and chemical evidence. Furthermore, in in vitro assays, compounds 2 and 4 (10μM) exhibited moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage. Graphical abstract

Source: Phytochemistry Letters - September 1, 2016 Category: Chemistry Source Type: research