Proton therapy demand wave drives expansion of Belgium ’ s IBA
(Reuters) – When Yves Jongen stood at the controls of his proton therapy machine 15 years ago to treat a cancer patient for the first time he was petrified. Now Jongen’s company IBA is hiring 400 engineers to cope with demand for the technology, increasing its workforce by a third, and expanding its production capacity to make up to 30 machines a year, from a maximum of 8 now. “It is such a responsibility to send a beam of potentially lethal particles into the body of a fellow human being. It is exciting but scary at the same time,” he said. Proton therapy made the front pages in Britain last year when 5-year-old Ashya King was removed from hospital by his parents, against the advice of doctors, and flown to Prague for treatment using an IBA-made machine. There are only 170 proton therapy treatment rooms worldwide to handle about 1% of radiation therapy patients. But there is already a consensus on the technology’s benefits for certain types of patients, such as children and young adults with spinal cord and base of brain tumours and a growing belief that it could also limit side effects. King’s family say he is now free of cancer. A spin-off of the Catholic University of Louvain’s nuclear physics department, IBA began life making cyclotrons to produce radioisotopes for hospitals and radiopharmaceutical companies. “We would sell one machine a year and enjoy ourselves a lot doing it,” said Jongen, 68, who founded ...
Supriya G. Mohile, M.D., M.S., an oncologist at the Wilmot Cancer Institute and trailblazer in the growing field of geriatric oncology, has been named the 2018 winner of the B.J. Kennedy Award by the American Society of Clinical Oncology (ASCO). She will deliver the B.J. Kennedy Lecture on June 4 at ASCO ’s annual meeting in Chicago.
Lung cancer has long been associated mostly with men. But a new study finds a disturbing trend among women, even among those who do not smoke. Tara Narula reports.
In conclusion, several confounding factors tested in this study can indeed modulate the transcriptional response of CCNG1 and PHPT1 and consequently can affect radiation exposure dose estimations but not to a level which should prevent the biomarkers’ use for triage purposes.
Tumor cells shed exosomes, which are released to the blood. Detecting tumor-derived exosomes containing RNA in plasma (liquid biopsy) is currently being investigated for early identification of occult metastases or relapses. Isolation of exosomes is laborious, resulting in low RNA yields. As a more robust (but less sensitive) alternative, the authors examined whether whole blood can be used as well. Tumor samples from nonmetastasized seminoma (n = 5) and colon cancer patients (n = 6) were taken during surgery. Whole-blood samples were taken before and 5–7 d after surgery. A whole genome mRNA microarray screening was ...
Ionizing radiation can induce genomic lesions such as DNA double-strand breaks whose incomplete or faulty repair can result in mutations, which in turn can influence cellular functions and alter the fate of affected cells and organ systems. Ionizing-radiation-induced sequence alterations/mutations occur in a stochastic manner, which contributes to an increased cancer risk in irradiated individuals. Ionizing radiation exposure, and particularly acute doses at high dose rates (as often observed in radiation accidents), induce alterations in the genome that in part will reflect specific characteristics of the DNA damage respo...
This article summarizes the results of 30 y of follow-up of cancer and noncancer effects in Ukrainian cleanup workers after the Chornobyl accident. The number of power plant employees and first responders with acute radiation syndrome under follow-up by the National Research Center for Radiation Medicine decreased from 179 in 1986–1991 to 105 in 2011–2015. Cancers and leukemia (19) and cardiovascular diseases (21) were the main causes of deaths among acute radiation syndrome survivors (54) during the postaccident period. Increased radiation risks of leukemia in the Ukrainian cohort of 110,645 cleanup workers ex...
In the biggest analysis of its kind, experts warn junk food, ready meals and red meat should be eaten only in moderation in favour of a diet that is rich in wholegrains, fruit and vegetables.
Researchers aren't sure why lung cancer incidence rates in women age 30 to 54 aren't falling as fast as in men the same age. CBS News' Meg Oliver reports.
A new report that reviews all the data from the last 30 years on diet, weight, physical activity, and cancer has come up with practical guidelines on lifestyle changes.Medscape Medical News
Researchers from the University of Gothenburg found that people who have a gastric band or bypass are 61 per cent less likely to develop melanoma, which can spread to other organs.
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