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Chickenpox Cases Down 85 Percent Since 2-Dose Vaccine Started: CDC

THURSDAY, Sept. 1, 2016 -- Chickenpox -- which is caused by the varicella-zoster virus -- has continued declining in the United States since 2006, when doctors began routinely recommending a second dose of chickenpox (varicella) vaccine, U.S. health...
Source: Drugs.com - Daily MedNews - Category: Journals (General) Source Type: news

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AbstractVaricella zoster virus (VZV) infection has been implicated in multiple sclerosis (MS), but direct causal involvement has been disputed. Nevertheless, knowledge of VZV exposure is important, given the risk of serious complications of first exposure while undergoing immunosuppressive treatment, in particular with fingolimod. We distributed questionnaires to MS clinic patients, requesting information about history of chickenpox, sibling/household/occupational exposure, history of zoster (shingles), and disease-modifying treatment. A random, proportionally representative sample of 51 patients that included patients wit...
Source: Journal of NeuroVirology - Category: Neurology Source Type: research
By Amanda MacMillan A few weeks after my 34th birthday, my husband and I went for a Saturday hike — a weekly ritual we’d started after moving to New York State’s Catskill Mountains region a few months earlier. I’d been feeling a bit under the weather, and I hoped the fresh autumn air would do me good. It didn’t. Later that night, I had chills and my skin felt strangely sensitive, like when you’re coming down with the flu. On top of that, it felt like I had pulled a muscle in my back or chest; when I breathed or stretched certain ways, I’d get shooting pains across my body. I blamed...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
CONCLUSION: Despite prior vaccination, seroimmunity in a large cohort of young adults unexposed to wild-type VZV failed to meet the estimated threshold for herd immunity. If vaccination in accordance with the current US VZV vaccination schedule is inadequate to maintain herd immunity, young adults not previously exposed to wild-type VZV may be at increased risk for varicella outbreaks. PMID: 28359621 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
​I want to reawaken awareness of a disappearing but highly contagious infectious disease — varicella. Thanks to immunizations for the wild-type varicella virus and shingles, or herpes zoster, younger health care providers are less aware of the appearance and clinical presentations of this viral infection.Presentations of this viral disease have markedly declined and presentations are often atypical since the advent of immunizations for varicella in 1995. This DNA virus within the herpes virus family is generally a mild childhood disease but can wreak physical havoc in adults, especially pregnant women. Immunosuppre...
Source: M2E Too! Mellick's Multimedia EduBlog - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
This article discusses the background, clinical manifestations, and management of herpes zoster ophthalmicus.
Source: Disease a Month - Category: Infectious Diseases Authors: Source Type: research
SummaryHerpes Simplex Virus (HSV) and Varicella‐zoster Virus (VZV) are two leading causes of sight‐threatening keratitis. They are able to become latent in nervous system, especially the trigeminal ganglia in which they can reactivate, thus producing new viral particles that finally reach the cornea.Episodes of HSV keratitis may occur spontaneously or following a triggering factor like immunosuppression (including topical steroids), topical inflammation and nerve injuries. Ocular surgery, which combines several of these factors, is a strong risk factor of HSV keratitis reccurence. In case of exposure to one of these tr...
Source: Acta Ophthalmologica - Category: Opthalmology Authors: Tags: Abstracts from the 2016 European Association for Vision and Eye Research Conference Source Type: research
Publication date: Available online 7 September 2016 Source:Pediatria Polska Author(s): Paweł Małecki, Anna Mania, Zbigniew Krasiński, Jerzy Harasymczuk, Katarzyna Jończyk-Potoczna, Katarzyna Mazur-Melewska, Paweł Kemnitz, Wojciech Służewski, Magdalena Figlerowicz Chickenpox is one of the most common childhood infectious diseases. Bacterial superinfections of the skin are the most common complications occuring in the disease. A 5-year-old boy was admitted to hospital owing to varicella-zoster virus infection complicated by purulent infection of the skin and subcutaneous tissue of the right leg. Before admission, sym...
Source: Pediatria Polska - Category: Pediatrics Source Type: research
This study aimed to determine the proportion of varicella non-immune pediatric healthcare workers (HCWs) of Pediatrics Department, King Chulalongkorn Memorial Hospital and to determine cost effective strategies to identify non-immune personnel. A cross-sectional study, using a self-administered questionnaire to determine history of chickenpox or 2-dose varicella vaccination was conducted. From a total of 699 HCWs, 653 HCWs (93%) including 145 physicians (22%), 297 nurses (46%) and 211 administrative staff (32%) responded to questionnaires. There were 475 HCWs (73%) who had a history of chickenpox, 58(9%) who had completed ...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research
Abstract Varicella-zoster virus (VZV) is a causative agent for chickenpox and zoster. Live attenuated vaccines have been developed based on Oka and MAV/06 strains. In order to understand the molecular mechanisms of attenuation, complete genome sequences of vaccine and wild-type strains were compared and single nucleotide polymorphism (SNP) was analyzed. ORF22 and ORF62 contained the highest number of SNPs. The detailed analysis of the SNPs suggested 24 potential vaccine-specific sites. All the mutational events found in vaccine-specific sites were transitional, and most of them were substitution of AT to GC pair. ...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
Authors: Majidy P, Khodabandehloo M, Azadi NA Abstract BACKGROUND AND OBJECTIVES: Varicella Zoster Virus (VZV) infection in pregnant women can cause complications for the mother and fetus. The aim of this study was to assess the immunity against VZV among young women before marriage. MATERIALS AND METHODS: In this cross-sectional study 250 women attending health centers in Sanandaj, Iran, for pre-marital medical check-up were randomly selected. The VZV IgG measured by ELISA and demographic characteristics of participants including their age, place of residence, number of siblings, occupation, education and hist...
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
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