Chickenpox Cases Down 85 Percent Since 2-Dose Vaccine Started: CDC

THURSDAY, Sept. 1, 2016 -- Chickenpox -- which is caused by the varicella-zoster virus -- has continued declining in the United States since 2006, when doctors began routinely recommending a second dose of chickenpox (varicella) vaccine, U.S. health...
Source: Drugs.com - Daily MedNews - Category: Journals (General) Source Type: news

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The skin is a tough tissue resistant to damage and therefore refractory to viral propagation. Varicella Zoster Virus (VZV) is a skin-tropic virus that causes chickenpox. Although very common, VZV infection can be life-threatening particularly in the immunocompromised. Therefore, understanding VZV-keratinocyte interactions is important to find new treatments beyond vaccination and anti-viral drugs. In VZV-infected skin, we observed focal up-regulation of the protease Kallikrein 6 (KLK6), and the ubiquitin-ligase MDM2 concomitant with Keratin 10 down-regulation.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Innate Immunity, Microbiology, Inflammation Source Type: research
Follow me on Twitter @RobShmerling Perhaps you heard the news recently that Lin-Manuel Miranda has shingles. Headlines announced this in a variety of ways: Hamilton creator Lin-Manuel Miranda is suffering from shingles (NY DailyNews) Lin-Manuel Miranda has shingles; must be quarantined from his baby (today.com) Lin-Manuel Miranda has shingles, regrets joke about blurred vision (CBS News). Without more information, these headlines might leave you wondering: is this a serious condition? Is it dangerous for children? Can it lead to blindness? What is shingles? The term “shingles” refers to a painful rash caused ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infectious diseases Skin and Hair Care Vaccines Source Type: blogs
(Natural News) A case study published in the journal Pediatric Dermatology looked at shingles cases that occurred in healthy children that were vaccinated for chickenpox. In the study, the authors looked at cases of shingles that were initially thought to be skin rashes. The authors looked at seven cases of children who contracted herpes zoster (shingles) at the...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
The goal of this study was to apply the varicella zoster virus (VZV) vaccine to patients with pediatric rheumatic diseases (PRD) at risk for severe chickenpox, without interrupting their current immunosuppress...
Source: Pediatric Rheumatology - Category: Rheumatology Authors: Tags: Research article Source Type: research
Conclusions:Varicella vaccination is not cost ‑effective in Iran in one‑dose and two‑dose scenario under the assumptions of this study in base case scenario according to the threshold of incremental cost per DALY averted less than three time of GDP per capita in Iran = US$ 14,292.One ‑dose vaccination program might be cost‑effective in upper scenario of epidemiological burden of varicella in sensitivity analysis.Keywords:Chicken pox, children, cost ‑effectiveness, Iran, varicella vaccination, varicella zostervirus
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
This study may provide new insight into the attenuating mutations associated with in vitro passaging of VZV. PMID: 29242077 [PubMed - as supplied by publisher]
Source: Virus Research - Category: Virology Authors: Tags: Virus Res Source Type: research
View Original Article Here: How Long Does Shingles Last In The Elderly? Shingles is a viral infection that follows a varicella-zoster infection, although it can take decades for symptoms of the secondary disease to emerge. The condition presents as a painful and blistering rash, but it is not life-threatening. According to the Center for Disease Control, there are nearly one million cases in the United States each year, and almost half of those cases are in older adults over age 60. Some people only see one instance of the illness, while others have recurring symptoms, but 30 percent of Americans will develop shingles at s...
Source: Shield My Senior - Category: Geriatrics Authors: Tags: Senior Safety Source Type: blogs
CONCLUSIONS: Data is consistent with that of the literature in other countries. The role of vaccination to prevent infection in children and adults is discussed. PMID: 29451634 [PubMed - in process]
Source: Salud Publica de Mexico - Category: Epidemiology Authors: Tags: Salud Publica Mex Source Type: research
AbstractVaricella zoster virus (VZV) infection has been implicated in multiple sclerosis (MS), but direct causal involvement has been disputed. Nevertheless, knowledge of VZV exposure is important, given the risk of serious complications of first exposure while undergoing immunosuppressive treatment, in particular with fingolimod. We distributed questionnaires to MS clinic patients, requesting information about history of chickenpox, sibling/household/occupational exposure, history of zoster (shingles), and disease-modifying treatment. A random, proportionally representative sample of 51 patients that included patients wit...
Source: Journal of NeuroVirology - Category: Neurology Source Type: research
By Amanda MacMillan A few weeks after my 34th birthday, my husband and I went for a Saturday hike — a weekly ritual we’d started after moving to New York State’s Catskill Mountains region a few months earlier. I’d been feeling a bit under the weather, and I hoped the fresh autumn air would do me good. It didn’t. Later that night, I had chills and my skin felt strangely sensitive, like when you’re coming down with the flu. On top of that, it felt like I had pulled a muscle in my back or chest; when I breathed or stretched certain ways, I’d get shooting pains across my body. I blamed...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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