First test of oral rabies vaccine brings hope to the world's rarest canid

A new study reports on field trials of the oral vaccine SAG2 in Ethiopian wolves, Africa's most threatened carnivore and the world's rarest canid. The trials are the first ever conducted in wild populations of an endangered carnivore.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Updated Date: Aug 13, 2018 EST
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
This article presented the World Health Organization's (WHO) recommendations on the use of Rabies vaccines excerpted from the Rabies vaccines: WHO position paper - April 2018 published in the Weekly Epidemiological Record [1] This position paper replaces the 2010 WHO position paper on rabies vaccines [2]. It presents new evidence in the field of rabies and the use of rabies vaccines, focussing on programmatic feasibility, simplification of vaccination schedules and improved cost-effectiveness. The recommendations concern the 2 main immunization strategies, namely vaccination for post-exposure prophylaxis and vaccination fo...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Guangxi is the province most seriously affected by rabies virus (RABV) in China. Those most affected by RABV each year are people in rural areas, where dogs are the main cause of human infection with the virus.
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
Changsheng Bio-technology Co Ltd, a vaccine maker at the center of a safety scandal in China, began falsifying production records for its rabies vaccine in April 2014, state news agency Xinhua reported on Tuesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: 1 October 2018Source: Preventive Veterinary Medicine, Volume 158Author(s): Fatima Yahiaoui, Moustafa Kardjadj, Younes Laidoudi, Hacène Medkour, Meriem Hind Ben-MahdiAbstractRabies is a neglected zoonotic disease. Several animal species can transmit rabies, but domestic dogs are the main reservoir implicated in rabies transmission to human and other susceptible animals. There is a scarcity of data regarding canine rabies in Algeria. Hence, this report is the first study that attempts to understand the epidemiology of dog rabies through a retrospective national study of rabies cases between 2010 and ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Rabies kills an estimated 20,000 people in India every year, according to the government's National Rabies Control Programme.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
by Mirjam Laager, C éline Mbilo, Enos Abdelaziz Madaye, Abakar Naminou, Monique Léchenne, Aurélie Tschopp, Service Kemdongarti Naïssengar, Timo Smieszek, Jakob Zinsstag, Nakul Chitnis Canine rabies transmission was interrupted in N’Djaména, Chad, following two mass vaccination campaigns. However, after nine months cases resurged with re-establishment of endemic rabies transmission to pre-intervention levels. Previous analyses investigated district level spatial heterogeneity of vaccination coverage, and dog density; and importation, identifying the latter as the primary factor for ra...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Abstract This infographic describes the transmission cycle of rabies virus in domestic dogs and the necessity of a One Health approach, integrating medical and veterinary interventions, to control and eliminate human rabies deaths. Rabies virus (RABV) causes an acute, fatal neurological infection in humans and other mammals, transmitted through the saliva of rabid animals via a bite or scratch. From the site of infection the virus travels along neurons to the central nervous system (CNS), where viral replication leads to symptoms and systemic spread. Once symptomatic, the disease is nearly 100% fatal. However, the...
Source: Trends in Microbiology - Category: Microbiology Authors: Tags: Trends Microbiol Source Type: research
This study aims to explore this knowledge gap, by providing factors and possible mechanisms that can explain children's involvement in the rabies post-exposure prophylaxis. This study was conducted in Bajawa district, Flores East Nusa Tenggara, Indonesia.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Type: Electronic/Moderated Poster Presentation Source Type: research
Background: Rabies is a viral neglected disease considered fatal, that affects mammals and with only 12 cases of survival reported in humans. Despite the existence of preventive vaccines, rabies still represents a serious public health problem, with a major impact in vulnerable populations around the world, causing about 55,000 human deaths per year. The membrane glycoprotein of the rabies virus (RVGP), specifically the ectodomain portion, has been intensively studied for the development of recombinant proteins, due to its ability to interact with neutralizing antibodies and induce immune responses.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 744 Source Type: research
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