Abstract # 1724 Depression and inflammation are independent predictors of fatigue in breast cancer survivors

Publication date: October 2016 Source:Brain, Behavior, and Immunity, Volume 57, Supplement Author(s): C. Xiao, A. Miller, J. Felger, D. Mister, T. Liu, M. Torres The purpose of this study was to examine predictors of fatigue in breast cancer survivors one-year post-radiotherapy. This cross-sectional, observational study enrolled 111 patients treated with breast conserving surgery followed by whole breast radiotherapy. Half of the patients received chemotherapy. The primary outcome variable was fatigue, measured by the Multidimensional Fatigue Inventory-20. Predictors included inflammation, age, race, marital status, smoking history, menopause status, endocrine treatment, cancer stage, depression (Inventory of Depressive Symptomatology–Self Reported), sleep problems (Pittsburgh Sleep Quality Index), and perceived stress (Perceived Stress Scale). Inflammation was assessed by plasma cytokines and/or their receptors using Multiplex ELISA and acute phase proteins (CRP) using a standard turbidimetric assay. Linear regression was employed to examine predictors of fatigue, and a mediation model using PROCESS SPSS was conducted to examine the association between depression, sleep problems, stress, inflammation and fatigue. At one-year post-radiotherapy, depression (B =0.65, p <0.001; B =0.73, P <0.0001; B =0.71, p <0.0001, for models with CRP, interleukin-1 receptor antagonist (IL1ra), or soluble tumor necrosis factor receptor2 (sTNFR2) respectively) and inflammation (...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research

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Publication date: Available online 14 August 2018Source: European Polymer JournalAuthor(s): Luanda Chaves LINS, Sébastien LIVI, Manuel MARÉCHAL, Jannick DUCHET-RUMEAU, Jean-François GÉRARDAbstractThe ability of different microstructures from ionic liquids (ILs) governed by anions and cations has been a source of curiosity for composite systems. In this present study, the structural behavior of polyvinylidene fluoride (PVDF) mixed with phosphonium- and imidazolium- based ionic liquids (1 wt%) combined with different counter anions was investigated. The effect of the chemical nature of the cation ...
Source: European Polymer Journal - Category: Chemistry Source Type: research
[News24Wire] A herbicide that is believed to cause cancer is widely in use in South Africa.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Abstract Construction of hybrid systems that combine the cancer treatment and diagnosis agents on a single platform, known as theranostic systems, have received great attentions in the field of nanobiomedicine. Here, construction and characterization of a new multifunctional hybrid theranostic system based on RGO, PDA, BSA, DTPA-Mn(II), and MTX constituents, is presented. Accordingly, GO is partially reduced and simultaneously functionalized by dopamine, leading to reduced graphene oxide/polydopamine, RGO-PDA system; and then, the bovine serum albumin protein (BSA) is grafted onto this system. The obtained system,...
Source: Biosensors and Bioelectronics - Category: Biotechnology Authors: Tags: Biosens Bioelectron Source Type: research
PROSTATE cancer risk could be lowered by losing weight or by avoiding pesticides, it ’s been claimed. But you could reveal your chances of developing prostate cancer symptoms by checking your fingers - this is what to look out for.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions: The heterogeneous effect of state legislation with regard to dense breast tissue on screening mammography follow-up by ultrasound may be explained by specific and unique characteristics of the approaches taken by a variety of states.
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
Publication date: Available online 13 August 2018Source: European Journal of Surgical OncologyAuthor(s): João Gonçalves Filho, Mark E. Zafereo, Faisal I. Ahmad, Iain J. Nixon, Ashok R. Shaha, Vincent Vander Poorten, Alvaro Sanabria, Avi Khafif Hefetz, K. Thomas Robbins, Dipti Kamani, Gregory W. Randolph, Andres Coca-Pelaz, Ricard Simo, Alessandra Rinaldo, Peter Angelos, Alfio Ferlito, Luiz P. KowalskiAbstractThe central compartment is a common site for nodal spread from differentiated thyroid carcinoma, often occurring in patients without clinical or ultrasonographic (US) evidence of neck lymph node metastasi...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Objectives: Previous retrospective studies demonstrated that circulating tumor cells (CTCs) subtypes correlate with overall survival in patients with pancreatic ductal adenocarcinoma (PDAC). Herein, we report results of a prospective observational study on CTCs dynamics to assess their clinical significance. Methods: The CLUSTER study is a prospective longitudinal study on PDAC CTCs dynamics (NCT02974764). Multiple peripheral blood samples were collected from 200 consecutively enrolled patients with presumed PDAC diagnosis. CTCs were isolated and characterized by immunofluorescence. Results: Two major CTCs subtypes...
Source: Annals of Surgery - Category: Surgery Tags: Papers of the 138Th ASA Annual Meeting Source Type: research
Conclusion: Margin positivity after resection for noninvasive IPMNs is primarily due to low grade dysplasia and is not associated with developing recurrence in the remnant pancreas or at the resection margin. Long-term surveillance is required for all patients, as a significant number of recurrences developed over 5 years after the index operation.
Source: Annals of Surgery - Category: Surgery Tags: Papers of the 138Th ASA Annual Meeting Source Type: research
Typical food store in Brazzaville, Congo. Credit: WHOBy Adelheid Onyango and Bibi GiyoseBRAZZAVILLE, Congo, Aug 14 2018 (IPS)When faced with a crisis, our natural reaction is to deal with its immediate threats. Ateka* came to the make-shift clinic with profuse diarrhoea: they diagnosed cholera. The urgent concern in the midst of that humanitarian crisis was to treat the infection and send her home as quickly as possible. But she came back to the treatment centre a few days later – not for cholera, but because she was suffering from severe acute malnutrition. Doctors had saved her life but not restored her health. And...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Africa Development & Aid Environment Food & Agriculture Headlines Health Humanitarian Emergencies Population Poverty & SDGs Source Type: news
Once again, the University of Texas'specialty cancer hospital is ranked number one by US News and World Report, even as the institution had high-profile struggles.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
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