Absence of poliovirus in apparently healthy school children in Bauchi state, Nigeria
Conclusions: Findings from this investigation indicate the absence of polioviruses in the children studied. This is an indication of good polio immunization coverage in these communities. However, more intensive and periodic surveillance is required to confirm the presence or exclude the absence of polioviruses in these communities and other parts of Nigeria.
In this study, we generated two recombinant RABVs, rERAG333E/NiVG and rERAG333E/NiVF, expressing the NiV Malaysian strain attachment glycoprotein (NiV-G) or fusion glycoprotein (NiV-F) gene based on the rERAG333E vector platform. Both rERAG333E/NiVG and rERAG333E/NiVF displayed growth properties similar to those of rERAG333E and caused marked syncytia formation after co-infection in BSR cell culture. Adult and suckling mice intracerebrally inoculated with the recombinant RABVs showed NiV-G and NiV-F expression did not increase the virulence of rERAG333E. Oral vaccination with rERAG333E/NiVG either singularly or combined wi...
Conclusions: A significant increase (P = .02) in Lyme arthritis cases was observed at Oishei Children's Hospital of Buffalo. Lyme arthritis may clinically present similarly to other forms of arthritis, such as oligoarticular juvenile idiopathic arthritis, so health care providers should be aware of distinguishing clinical features, which include rapid onset of swelling and patient age. Because the geographic area of endemic Lyme disease is expanding, all health care providers need to be aware of Lyme arthritis as a possible diagnosis. PMID: 31819695 [PubMed]
Conclusion: Vulnerable populations were found to be less knowledgeable on risk factors and they had poor practice. Education had significant impact on knowledge and attitude of urban population; however, their practice did not improve with education. PMID: 31815581 [PubMed - as supplied by publisher]
Authors: Abstract "My biggest motivation is the discovery of new therapeutics to save lives. The most significant scientific advance of the last 100 years has been the discovery of polio vaccine …" Find out more about Yanli Zhao in his Author Profile. PMID: 31816177 [PubMed - in process]
The authors regret an error in Figure 3, “Local failure among patients with parameningeal rhabdomyosarcoma by a) cumulative cyclophosphamide dose and b) cyclophosphamide dose-intensity.” An incorrect figure was initially included, in which the figure legend for Figure 3a was mislabeled. The correct figure, which shows the correct figure legend, is shown below. The authors apologize for any inconvenience caused.
Vector-Borne and Zoonotic Diseases, Ahead of Print.
Mr Yohei Sasakawa, chairman of the Nippon Foundation and Sasakawa Health Foundation and WHO Goodwill ambassador. Credit : Crystal Orderson / IPSBy Rafiqul Islam and Crystal OrdersonDHAKA, Bangladesh, Dec 11 2019 (IPS) Leprosy is not a curse but should be detected and treated early, Bangladeshi Prime Minister, Sheikh Hasina, has told delegates at a gathering in her country’s capital to discuss the elimination of the disease. “In the past, it was thought that leprosy was a curse. But it was not a curse at all. The disease is caused by bacteria (Mycobacterium Leprae). We should fight it through research,” H...
Date: Tuesday, 12 17, 2019; Speaker: Dr. Erin Beck, NINDS; Dr. Kenneth Tyler, University of Colorado School of Medicine; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
AbstractA regional epidemic of aseptic meningitis caused by echovirus 30 (E30) occurred in Hokkaido, Japan, during the period of August-December 2017. To investigate their phylogenetic relationship to other human enteroviruses, we determined the complete genomic nucleotide sequences of isolates from this outbreak. Phylogenetic analysis of the viral capsid protein 1 gene showed that the strains were most closely related to E30 strains detected in Germany, France, and Russia in 2013. In contrast, the region encoding the viral protease and the RNA-dependent RNA polymerase had a close phylogenetic relationship to non-E30 enter...
A 3-month-old Malaysian infant has been diagnosed with polio, the first case reported in the country in nearly three decades, a top health official said on Sunday.Reuters Health Information