Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients

Conclusion
Utilizing metabolic profiling in two independent prospective cohorts of patients undergoing ICD implantation for primary prevention of SCD, we identified several novel amine markers that were associated with appropriate shock and mortality. These findings shed insight into the potential biologic pathways leading to adverse events in ICD patients. Further studies are needed to confirm the prognostic value of these findings.

Source: Europace - August 30, 2016 Category: Cardiology Authors: Zhang, Y., Blasco-Colmenares, E., Harms, A. C., London, B., Halder, I., Singh, M., Dudley, S. C., Gutmann, R., Guallar, E., Hankemeier, T., Tomaselli, G. F., Cheng, A. Tags: Sudden death and ICDs Source Type: research