Mesothelioma Clinical Trial for Tazemetostat Launches in US

City of Hope cancer center thoracic oncologist Dr. Marianna Koczywas explains the workings of tazemetostat — the latest drug tested in a mesothelioma clinical trial — with the lock and key metaphor. “You have a specific [cancer] key, and a specific keyhole it goes through. If you can lock that keyhole, you can lock it out,” Koczywas told Asbestos.com. “These malignant cells rely on a pathway for growth and division so you try and block that specific pathway.” Koczywas is principal investigator for the mesothelioma clinical trial at the City of Hope National Medical Center in Los Angeles, one of eight locations in the U.S. recruiting patients for this promising phase II trial. The other cancer centers hosting the clinical trial include: University of Maryland Medical Center in Baltimore Massachusetts General Hospital in Boston Mayo Clinic in Rochester, Minnesota Memorial Sloan Kettering Cancer Center in New York MD Anderson Cancer Center in Houston UCLA Comprehensive Cancer Center University of California San Francisco Medical Center Several centers in the U.K. and France are also hosting the trial. “We’re opening this trial because we believe it is promising,” Koczywas said. “We still have very limited options for patients with mesothelioma and welcome any therapy with potential to benefit the patients, prolong life and provide better quality of life. We think this drug can do that.” Effectiveness of Tazemeto...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: cancer treatment city of hope cancer center clinical trials at memorial sloan kettering clinical trials in california malignant pleural mesothelioma treatment marianna koczywas mesothelioma clinical trial tazemetostat Source Type: news

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