Nocturia Work Productivity and Activity Impairment Compared with Other Common Chronic Diseases
ConclusionsThe overall work productivity impairment as a result of nocturia is substantial and was found to be similar to impairment observed as a result of several other more frequently researched common chronic diseases. Greater awareness of the burden of nocturia, a highly bothersome and prevalent condition, will help policy makers and healthcare decision makers provide appropriate management of nocturia.
Authors: Chu Y, Ge W, Wang X Abstract MicroRNAs (miRNAs) play crucial roles in the pathogenesis of neuropathic pain. The present study investigated the effects of miR-448 on the progression of neuropathic pain in a rat model of chronic constriction injury (CCI) of the sciatic nerve. Reverse-transcription quantitative polymerase chain reaction was conducted to detect the gene expression. The paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) were used to assess the pain threshold. The protein expression levels of interleukin (IL)-6, IL-1β and tumor necrosis factor-α (TNF-α) were detecte...
Publication date: 1 January 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 185Author(s): Furqan A. Maulvi, Lakshmi V. Pillai, Kajal P. Patel, Ankita R. Desai, Manish R. Shukla, Ditixa T. Desai, Hetal P. Patel, Ketan M. Ranch, Shailesh A. Shah, Dinesh O. ShahAbstractLidocaine is widely used as a local anaesthetic in the clinical practice to manage pre- and post-operative pain, skin burns, etc. However, the short duration of action (
Publication date: 1 January 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 185Author(s): Fazlurrahman Khan, Dung Thuy Nguyen Pham, Sandra Folarin Oloketuyi, Panchanathan Manivasagan, Junghwan Oh, Young-Mog KimAbstractBiofilm formed by several pathogenic bacteria results in the development of resistance against antimicrobial compounds. The polymeric materials present in the biofilm architecture hinder the entry of antimicrobial compounds through the surface of bacterial cells which are embedded as well as enclosed beneath the biofilm matrix. Recent and past studies explored the alternative approaches to inhibit ...
Publication date: January 2020Source: Brain, Behavior, and Immunity, Volume 83Author(s): Elisa Brietzke, Linda Booij, Andrea Wieck, Alessandro Ricci, Claudio N. Soares, Nasreen Roberts, Sarosh Khalid-Khan
Conclusions: These findings suggest that among MDD patients, early experiences of emotional and physical abuse and neglect is associated with difficulties in describing feelings in adulthood. PMID: 31808358 [PubMed - as supplied by publisher]
All people are the same; only their habits differ. ~ Confucius This is a post about what keeps us stuck and sets us free, about the good news behind bad luck, and the wrong way to want the right thing: It’s about our habits. Human beings are creatures of habit — even emotionally. But why is this? Why do we fall into routines? And why is it so hard to break a habit? The short answer is something called set point. You’re probably familiar with this idea if you have ever been on a diet or had a new year’s resolution. They both start well. You are going to make a change in your life and you are ready fo...
Many patients with cognitive impairment have anxiety or depression, but standard treatments are difficult for people with memory issues.
(NYU Langone Health / NYU School of Medicine) A computer betting game can help predict the likelihood that someone recovering from opioid addiction will reuse the pain-relieving drugs, a new study shows.
Publication date: 7 December 2019Source: New Scientist, Volume 244, Issue 3259Author(s): Clare Wilson
This study aimed to examine the association between family functioning and suicide among the elderly in rural China. This 1:1 paired case-control psychological autopsy study included 242 suicides at age 60 or more and an equal number of controls matched on...
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