Saving six: Life before and after transplant

An organ transplant is a life-changing event extending far beyond the operating room, the clinics and the hospital walls. Read about five children, one young adult and their families, whose lives were forever changed by the Pediatric Transplant Center at Boston Children’s Hospital. Lydia’s liver transplant, a mom’s gift Dawn Cavanagh gave her daughter life twice — first when she was born and, again, when she gave 13-year-old Lydia a piece of her liver last summer. The donor-approval process, which occurs with Boston Children’s partner Lahey Hospital &Medical Center, required hours of medical screening, including an interview with a social worker, who asked if Dawn expected anything in return for being Lydia’s liver donor. “And I said, ‘Of course I expect something,’” explains Dawn. “’I expect her to live a long and happy life, and I expect her to be with me for a long time.’” More than a year after her liver transplant, for Lydia’s birthday, Aug. 1, the Cavanagh family went on Lydia’s Make-A-Wish trip, a Disney cruise to the Bahamas. “We had so much fun,” says Dawn. “She’s a happy kid. She has dreams. She wants to be a transplant nurse, and she wants to work on 10 South at Boston Children’s Hospital.”  A birthday wish granted Lucas and Dr. Vakili Lucas St. Onge was a very sick boy when he was born. Diagnosed in utero with severe s...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories double lung transplant ECMO heart failure heart transplant Heart transplant program heart-lung transplant Heung Bae Kim Intestine and Multivisceral Transplant Program Khashayar Vakili kidney transplant Kidney Source Type: news

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This study involved three experimental steps. The first one characterized specific surface areas of biochars and ACs. The second one assessed CLD-availability of contaminated artificial soils (50 μg g-1 of Dry Matter) amended with 5% of biochar or AC (mass basis). The third one assessed CLD bioavailability of those artificial soils through an in vivo assay. To limit ethically the number of animals, selections of the most promising media were performed between each experimental steps. Forty four castrated male 40-day-old piglets were exposed during 10 day by amended artificial soils according to their group (n...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
HIGH blood pressure and high cholesterol work hand in hand to increase the risk of heart disease. Dietary habits have a huge influence over these, so there are six foods swaps you should make.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Iglesias Jorquera E, Tomás Pujante P, Ruiz García G, Vargas Acosta ÁM, Pons Miñano JA Abstract Type III glycogen storage disease (GSD-III) is an autosomal recessive disorder due to the deficiency of the glycogen debrancher enzyme. 80% of the patients have hepatic and muscular involvement (IIIa), compared to 15% with only liver involvement (IIIb). As the life expectancy improves in these patients, the possible liver complications are better understood. PMID: 30318896 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
CONCLUSION: Sheathless intervention is feasible with several potential advantages, including short procedure time, minimal contrast volume, and reduced radiation exposure. Finally, the lower profile at the access site may result in fewer complications. PMID: 30319012 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Authors: Barzel E, Larkin JW, Marcus A, Reviriego-Mendoza MM, Usvyat LA, Sor M, Maddux FW Abstract INTRODUCTION: Hemodialysis patients with an arteriovenous fistula can use buttonhole techniques for cannulation. Although buttonholes generally work well, patients may report difficult and painful cannulation, and buttonholes may fail over time. We aimed to assess the effectiveness of tract dilation in treatment of failing buttonholes. METHODS: We retrospectively analyzed data from patients treated with buttonhole tract dilation at an outpatient vascular access center between January 2013 and August 2015. RESU...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Conclusions: The SOC activities were inhibited in BM-derived EPCs of MCT-treated rats. These results may be associated with the depressed expression of Orai3, TRPC1, TRPC3, and TRPC6, which are major mediators of SOC. PMID: 30320134 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Echocardiography, EarlyView.
Source: Echocardiography - Category: Cardiology Authors: Source Type: research
AbstractPurpose of ReviewThis paper presents an overview of the current developments in the perioperative biliary atresia (BA) treatment.Recent FindingsBiliary atresia is a rare cholangiopathy and the most common indication for pediatric liver transplantation. Kasai portoenterostomy is the primary therapy, leading to sufficient biliary drainage in 20 –30% of patients with native liver. Multiple strategies in preoperative, operative, and postoperative care were tested to improve survival with native liver (SNL). Screening methods, centralization of care to specialized centers, laparoscopic Kasai procedure, and adjuvan...
Source: Current Pathobiology Reports - Category: Laboratory Medicine Source Type: research
Abstract: Although cardiac evaluation before kidney transplantation commonly focuses on coronary artery disease, a comprehensive pretransplant cardiac evaluation must consider other prognostically important cardiac conditions including functional and structural heart disease. Pulmonary hypertension (PH) is increasingly recognized among patients with kidney failure and may be driven by left heart failure, high cardiac output from arteriovenous fistula, hypoxic lung diseases, and metabolic derangements associated with renal disease. In this article, we examine several key concepts and controversies relevant to optimizing the...
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science-General Source Type: research
Abstract Pulmonary veno-occlusive disease (PVOD) is rare condition which can lead to severe pulmonary hypertension, right ventricular dysfunction, and cardiopulmonary failure. The diagnosis of PVOD can be challenging due to its nonspecific symptoms and its similarity to idiopathic pulmonary arterial hypertension and interstitial lung disease in terms of diagnostic findings. This case describes a 57 year old female patient who presented with a 5-month history of progressive dyspnea on exertion and nonproductive cough. Workup at another hospital was nonspecific and the patient underwent surgical lung biopsy due to c...
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Respir Med Case Rep Source Type: research
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