Biosynthesis of size-controllable silver nanoparticles and their in vitro antidiabetic activity

Publication date: Available online 29 August 2016 Source:Environmental Toxicology and Pharmacology Author(s): Rui-xia Liu A simple biosynthetic approach for the size-controllable production of silver nanoparticles (AgNPs) using the leaf extract of Cinnamomum tsoi as a reducing and capping agent was developed. The polyphenolic functionalities present in the extract were responsible for synthesis and stabilization of the AgNPs. The size and morphology of the AgNPs were effectively adjusted by changing the volume of the extract. The AgNPs were characterized by X-ray diffraction, UV-visible spectroscopy, transmission electron microscopy, selected area electron diffraction, dynamic light scattering, and Fourier transform infrared spectroscopy techniques. The prepared AgNPs significantly inhibited the α-amylase and α-glucosidase enzymes in a dose-dependent manner. This method can replace the chemical approaches for size-controlled AgNP synthesis that are currently being used. Graphical abstract
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research