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Scientists find drugs for cancer, hepatitis C can kill Zika in petri dish. But will they work in humans?

Scientists have discovered three existing drugs — used for cancer, hepatitis C and for parasitic infections — that they say appear promising against the Zika virus. The experiments were conducted only in lab-grown human cells in petri dishes, but the results were dramatic. Zika is so devastating that the damage it does has been thought to be irreversible. But the researchers […]Related:Pocket Porn: Why Anthony Weiner can’t seem to stop sextingMore parents believe vaccines are ‘unnecessary,’ while a mumps outbreak growsSingapore Zika cases rise to 56 at one construction site; Malaysia starts border screening
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news

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The Daily Mail's resident GP answers your queries on everything and anything. This week,he deals with the effects of airport scanners, allergies chronic pain.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: We report a high seroprevalence rate and several potential risk factors of HEV infection in a large HIV cohort from Yunnan province in China. Further research on identification of the circulating HEV strains and the clinical outcome of this patient population is required. This article is protected by copyright. All rights reserved
Source: Journal of Medical Virology - Category: Virology Authors: Tags: Research Article Source Type: research
AbstractWe generated epidemiological information on the prevalence of nematode parasites and possible resistance/resilience of goats in three areas, Bati, Shinille, and Borana, of Ethiopia. A total of 350 breeding does were randomly selected and monitored for one year. Fecal egg counts (FEC), packed cell volume (PCV), body weight (BW), body condition score (BC), and fecal larvae identification were done. In Borana, the long rainy season had higher FEC, lower PCV, lower BC, and smaller BW compared to dry and short rainy seasons (p 
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
This study aimed to describe the epidemiological, clinical, and pathological aspects of an outbreak of poisoning byKalanchoe blossfeldiana in cattle in the semiarid region of Pernambuco, Brazil. Epidemiological and clinical data were obtained from the owner and veterinarian during technical visits. Prunings of this plant were disposed of in a pasture with a shortness of forage. Seventeen cattle had clinical signs, and thirteen died 4 –5 days after the first clinical signs were observed. Clinical signs and gross and histological lesions include gastrointestinal, cardiovascular, and neuromuscular disorders.Kalanch...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
AbstractBayesian Additive Regression Trees (BART) is a statistical sum of trees model. It can be considered a Bayesian version of machine learning tree ensemble methods where the individual trees are the base learners. However, for datasets where the number of variablesp is large the algorithm can become inefficient and computationally expensive. Another method which is popular for high-dimensional data is random forests, a machine learning algorithm which grows trees using a greedy search for the best split points. However, its default implementation does not produce probabilistic estimates or predictions. We propose an a...
Source: European Journal of Applied Physiology - Category: Physiology Source Type: research
Chagas disease is included in the neglected tropical diseases list and is endemic to 21 Latin American countries. The two drugs currently available for treating Chagas disease are nifurtimox and benznidazole and both result in many significant side effects. The study describes the synthesis and biological evaluation of 3,5-disubstituted isoxazoles. Isoxazoles were obtained by reaction of flavones and hydroxylamine and either alkylated at the free hydroxyl group and/or nitrated at the isoxazole ring. These compounds were evaluated for their in vitro anti-Trypanosoma cruzi activity against trypomastigote and amastigote forms...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
Old age is a risk factor for cancer development in humans and animals, and studies have shown that tumors in animals are acceptable models for studying human cancers, considering the similarities between their factors. This work was conducted in a 53-year-old captive female common hippo (Hippopotamus amphibious) with a left leg tumor and metastatic mass. Histopathological and immunohistochemical analyses were carried out with a final diagnosis of a high grade pleomorphic sarcoma. A proteomic study using mass spectrometry was added in order to identify further aspects of the primary tumor and metastasis which could improve ...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
New J. Chem., 2018, Accepted Manuscript DOI: 10.1039/C7NJ04633B, PaperLina Cellante, Roberta Costa, Ilaria Monaco, GIOVANNA CENACCHI, Erica Locatelli Fisher esterification reaction has been exploited for linking a peptide (Chlorotoxin) onto the surface of nanocellulose by using a Bronsted acid ionic liquid both as solvent and catalyst. Indeed, cellulose... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Dalton Trans., 2018, Advance Article DOI: 10.1039/C7DT04093H, PaperArif Gulzar, Jiating Xu, Liangge Xu, Piaoping Yang, Fei He, Dan Yang, Guanghui An, Mohd Bismillah Ansari The disulfide bond (-S-S-) is an enormously valuable functional group in a variety of chemical and biological agents that display effective reactivity or biological activities (e.g., antitumor activities). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
CANCER symptoms vary depending on which part of the body is affected by the tumour. Back pain and weight loss could be a sign of the bladder disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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