Scientists find drugs for cancer, hepatitis C can kill Zika in petri dish. But will they work in humans?

Scientists have discovered three existing drugs — used for cancer, hepatitis C and for parasitic infections — that they say appear promising against the Zika virus. The experiments were conducted only in lab-grown human cells in petri dishes, but the results were dramatic. Zika is so devastating that the damage it does has been thought to be irreversible. But the researchers […]Related:Pocket Porn: Why Anthony Weiner can’t seem to stop sextingMore parents believe vaccines are ‘unnecessary,’ while a mumps outbreak growsSingapore Zika cases rise to 56 at one construction site; Malaysia starts border screening
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 16 November 2018Source: Seminars in Cancer BiologyAuthor(s): Besa Xhabija, Benjamin L. KidderAbstractEpigenetic regulation of chromatin plays a critical role in controlling stem cell function and tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation of histone 3 lysine 4 (H3K4), is important for embryonic stem (ES) cell differentiation, and is a critical regulator of the H3K4-methylome during early mouse embryonic pre-implantation stage development. KDM5B is also overexpressed, amplified, or mutated in many cancer types. In cancer cells, KDM5B regulates e...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 16 November 2018Source: Cancer GeneticsAuthor(s): Jennelle C. Hodge, David Bosler, Lauren Rubinstein, Navid Sadri, Shashirekha ShettyAbstractThe inv(3)(q21q26.2) altering a single chromosome 3 homolog is an established myeloid malignancy-associated entity. Comparatively, double inv(3) cases involving both homologs are exceedingly rare with 13 reports across AML, CML and MDS. This scarcity was confirmed by finding only 2 new cases out of 34,898 bone marrows collected during a 55 year period at a large medical center (0.0005%). The double inv(3) was detected by karyotype and confirmed by FI...
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
New research published inNeuro-Oncology examines the controversial link between intracranial volume and high-grade glioma.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Publication date: Available online 15 November 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Funda Üstün, Burcu Tokuc, Ebru Tastekin, Gülay DurmuĊŸ AltunAbstractAimIn lung cancer, axillary lymph node metastases (ALM) are rare, and according to the 8th grading system, it is classified as M1b disease. The aim of this study is to evaluate (i) the presence of ALM, and (ii) the effect of the primary tumors characteristics on the development of ALM.MethodsWe performed a descriptive cross-sectional study, with retrospective revision, to identify ALM.ResultsTh...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Authors: Gong W, Qi X Abstract Frailty is characterized by a state of vulnerability to poor resolution of homoeostasis after a stressor event and is a consequence of age-related decline in many physiological systems during a lifetime. To access the association between frailty and delayed recovery of gastrointestinal function in patients undergoing elective colorectal cancer resections, 241 patients who had undergone elective colorectal cancer resections from July 2015 to August 2017 were investigated. The association of frailty with delayed recovery of gastrointestinal function, length of stay (LOS), and whether or...
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
CONCLUSIONS: Endobronchial targeting of peripheral airway targets is feasible using existing open-source technology. Notwithstanding the shortcomings of current commercial platforms, technological improvements in EM tracking and registration accuracy fostered by open-source technology may provide the impetus for widespread clinical uptake of electromagnetic navigation in bronchoscopy. PMID: 30428748 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
Linda Woolley, 73, was diagnosed with 'likely' kidney cancer at the University of Colorado Hospital in March. She had both organs removed before doctors realized she was cancer-free.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: NDM-1-producing HMKP ST1764 isolates were identified; this is the first report worldwide on an outbreak of nosocomial infection caused by these isolates. Effective surveillance and strict infection control strategies should be implemented to prevent CR-HMKP dissemination. PMID: 30430779 [PubMed - in process]
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research
Authors: Lerner AD, Feller-Kopman D PMID: 30433839 [PubMed - as supplied by publisher]
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
An 11th child has died in less than four weeks at a New Jersey rehabilitation center, one of 34 young patients with compromised immune systems to have been infected by a viral outbreak, state health officials said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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