Total Skin Electron Beam Therapy in the Treatment of Mycosis Fungoides: a review of Conventional and Low-Dose Regimens

Mycosis fungoides (MF) is the most prevalent subtype of cutaneous T-cell lymphoma, which is characterized by the proliferation of CD4+ T-cells. While often an indolent disease, most patients eventually develop progression from isolated patches to tumors and finally nodal or visceral involvement. Treatment choice is largely based on disease burden, though prognostic factors such as disease stage, patient age, and extra-cutaneous involvement must be taken into consideration. Radiation therapy represents one of the most effective therapeutic modalities in the treatment of MF.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Review Article Source Type: research