Togo slaughters 11,500 chickens after H5N1 bird flu outbreak

LOME (Reuters) - Togolese authorities said on Saturday they had slaughtered 11,500 chickens in response to an outbreak of H5N1 bird flu at two farms in the capital Lome and the town of Adetikope, about 25 km north of Lome.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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ahesh Influenza A viruses (IAVs) are a major cause of respiratory illness and are responsible for yearly epidemics associated with more than 500,000 annual deaths globally. Novel IAVs may cause pandemic outbreaks and zoonotic infections with, for example, highly pathogenic avian influenza virus (HPAIV) of the H5N1 and H7N9 subtypes, which pose a threat to public health. Treatment options are limited and emergence of strains resistant to antiviral drugs jeopardize this even further. Like all viruses, IAVs depend on host factors for every step of the virus replication cycle. Host kinases link multiple signaling pathways ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Abstract Waterbirds are the main reservoir for low pathogenic avian influenza A viruses (LPAIV), from which occasional spillover to poultry occurs. When circulating among poultry, LPAIV may become highly pathogenic avian influenza A viruses (HPAIV). In recent years, the epidemiology of HPAIV viruses has changed drastically. HPAIV H5N1 are currently endemic among poultry in a number of countries. In addition, global spread of HPAIV H5Nx viruses has resulted in major outbreaks among wild birds and poultry worldwide. Using data collected during these outbreaks, the role of migratory birds as a vector became increasin...
Source: Adv Data - Category: Epidemiology Authors: Tags: Adv Virus Res Source Type: research
Asian Openbills, Anastomus oscitans, have long been known to migrate from South to Southeast Asia for breeding and nesting. In Thailand, the first outbreak of H5N1 highly pathogenic avian influenza (HPAI) infecti...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
Authors: Mandil A, Bresee J, Tageldin MA, Azad TM, Khan W Abstract Infectious diseases continue to represent a significant threat to global health security, particularly in the context of increasing globalization, interconnectedness and interdependence. Chief among such threats are influenza viruses and other respiratory pathogens, such as Middle East Respiratory Syndrome coronavirus (MERS-CoV), because of their risk of high transmissibility and acuity of illness. Annual epidemics of seasonal influenza cause an estimated 3-5 million cases of severe illness and more than 500 000 deaths, with the prospect of pandemic...
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
This study records varying clinical and pathological manifestations of HPAI in ducks and quails following natural infection with the same strain of the virus. PMID: 30303027 [PubMed - as supplied by publisher]
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research
Abstract Bird to human transmission of high pathogenicity avian influenza virus (HPAIV) poses a significant risk of triggering a flu pandemic in the human population. Therefore, vaccination of susceptible poultry during an HPAIV outbreak might be the best remedy to prevent such transmissions. To this end, suitable formulations and an effective mass vaccination method that can be translated to field settings needs to be developed. Our previous study in chickens has shown that inhalation of a non-adjuvanted dry powder influenza vaccine formulation during normal breathing results in partial protection against lethal ...
Source: European Journal of Pharmaceutics and Biopharmaceutics - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharm Biopharm Source Type: research
Abstract The limited protection of current commerical vaccines necessitates the investigation of novel vaccine strategies for unpredictable outbreaks. To investigate the feasibility of using vaccines derived from Group 1 influenza A virus to induce broadly cross-reactive immune responses against multiple influenza subtypes, we tested a panel of sequential 4-dose immunization regimens in mice. Mice were treated with inactivated (seasonal H1N1, pandemic H1N1 and H5N1) and vaccinia virus-based H5N1 live-attenuated vaccines in different combinations. Mice were then challenged by viruses of either Group 1 (H1N1) or Gro...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
Publication date: Available online 19 September 2018Source: Preventive Veterinary MedicineAuthor(s): Renata Retkute, Chris P. Jewell, Thomas P. Van Boeckel, Geli Zhang, Xiangming Xiao, Weerapong Thanapongtharm, Matt Keeling, Marius Gilbert, Michael J. TildesleyAbstractThe Highly Pathogenic Avian Influenza (HPAI) subtype H5N1 virus persists in many countries and has been circulating in poultry, wild birds. In addition, the virus has emerged in other species and frequent zoonotic spillover events indicate that there remains a significant risk to human health. It is crucial to understand the dynamics of the disease in the pou...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
In this study we perform simulations of a previously developed H5N1 influenza transmission model framework, fitted to two separate histori cal outbreaks, to assess specific control objectives related to the burden or duration of H5N1 outbreaks among poultry farms in the Dhaka division of Bangladesh. In particular, we explore the optimal implementation of ring culling, ring vaccination and active surveillance measures when presuming dis ease transmission predominately occurs from premises-to-premises, versus a setting requiring the inclusion of external factors. Additionally, we determine the sensitivity of the management a...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
Since March 2013, when the avian influenza A(H7N9) virus infection was first detected in humans, a total of 1567 laboratory-confirmed human cases, including at least 615 deaths1, have been reported to WHO (Figure 1) in accordance with the International Health Regulations (2005). In the latest wave (the 6th wave since Oct 2017), only three human cases have been detected; meanwhile there have been generally fewer A(H7N9) virus detections in poultry and environment samples, according to various reports from mainland China and China, Hong Kong SAR. WHO has been monitoring the situation, and conducting risk assessments2 through...
Source: WHO Avian Influenza - Category: Infectious Diseases Tags: avian influenza [subject], bird flu, avian flu, fowl plague, influenza in birds, avian bird flu, h5n1, disease outbreaks [subject], outbreak, outbreaks, epidemics, pandemic, disease control, influenza [subject], flu, seasonal influenza, pandemic influenza Source Type: news
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