The Vasopressin Type-2 Receptor and Prostaglandin Receptors EP2 and EP4 can Increase Aquaporin-2 Plasma Membrane Targeting Through a cAMP Independent Pathway.
In conclusion, this study demonstrates that although direct stimulation with cAMP causes AQP2 membrane targeting, cAMP is not necessary for receptor-mediated AQP2 membrane targeting and Gs coupled receptors can also signal through an alternative pathway that increase AQP2 membrane targeting.
PMID: 27558562 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Olesen ET, Moeller HB, Assentoft M, MacAulay N, Fenton RA Tags: Am J Physiol Renal Physiol Source Type: research
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