Drug –Drug Interactions, Effectiveness, and Safety of Hormonal Contraceptives in Women Living with HIV
AbstractFamily planning options, including hormonal contraceptives, are essential for improving reproductive health among the more than 17 million women living with HIV worldwide. For these women, prevention of unintended pregnancy decreases maternal and child mortality, as well as reduces the risk of perinatal HIV transmission. Similarly, treatment of HIV with antiretroviral therapy (ART) is essential for reducing morbidity and mort ality among HIV-positive individuals, as well as preventing HIV transmission between sexual partners or from mother to child. Importantly, despite the benefits of hormonal contraceptives, barriers to effective family planning methods exist for HIV-positive women. Specifically, drug–drug interactio ns can occur between some antiretroviral medications and some hormonal contraceptives, which may influence both contraceptive efficacy and tolerability. In addition, safety concerns have been raised about the impact of hormonal contraceptives on HIV disease progression, tolerability, and the risk of female-to-male HIV transmission. This review article summarizes the potential for drug–drug interactions, tolerability, and contraceptive effectiveness when hormonal contraceptives are combined with ART. In addition, the evidence surrounding the influence of hormonal contraceptives on HIV transmi ssion and HIV disease progression in women living with HIV are summarized.
Sperm DNA damage reduces pregnancy rates in couples undergoing in vitro fertilization (IVF). Because it has been shown that testicular sperm have lower DNA damage than ejaculated sperm, it is an attractive idea to consider using testicular sperm for IVF for men with high sperm DNA damage. In fact, there are multiple centers throughout the world now offering sper m retrieval for IVF to manage this condition. However, there is insufficient evidence to conclude that testicular sperm improves pregnancy/live birth rates. Further studies are required before offering sperm retrieval as a standard of care to manage high sperm DNA damage.
INTRODUCTION: Dating violence is a common problem among adolescents, particularly among Latinx pregnant and parenting adolescents, and can be detrimental to adolescent parents and their children. However, little is known about whether different forms of da...
Conditions: Covid19; Pregnancy Related Intervention: Biological: Evaluation of blood results of covid 19 positive pregnant patients Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Active, not recruiting
Conditions: Overweight and Obesity; Pregnancy Related Intervention: Behavioral: Healthy Habits in Pregnancy and Beyond Sponsors: Queen's University, Belfast; University of Leeds; University College, London; Belfast Health and Social Care Trust; Western Health and Social Care Trust; Sligo General Hospital; Our Lady of Lourdes Hospital, Drogheda Not yet recruiting
Cosmetic devices using non-ionizing radiation (NIR) are increasingly available for people who wish to modify their appearance for aesthetic purposes. There are a wide range of NIR modalities used for cosmetic procedures, including devices that use optical radiation (laser, intense pulsed light, and light-emitting diode), electromagnetic fields, and ultrasound. Common procedures involving the application of NIR include epilation, skin rejuvenation, body sculpting and contouring, treatment of vascular and skin lesions, tattoo removal, and scar reduction. The majority of research on the use of NIR cosmetic devices has focused...
Despite the medical advances that have occurred in recent times, the risks associated with pregnancy have not declined, and in fact, maternal mortality is on the increase. What needs to be done?American Journal of Public Health
Many women have a period tracker or fertility app on their smartphone to monitor their menstrual cycle or help them plan or prevent pregnancy but a new review finds that they could be misleading women.
A majority of pregnant women who are diagnosed with coronavirus don't experience more severe illness than the general population, according to a new study.
[The Conversation Africa] Disrespect and abuse during childbirth are a violation of women's human rights. Women deserve care that maintains their dignity, ensures their privacy and confidentiality and is free from mistreatment and discrimination.