What's in the Literature?

Abstract: The Guillain–Barré syndrome (GBS) is one of the few neuropathies well known to the general public, in part because of its association with swine flu vaccinations in 1976. GBS has again reached the general public with its possible association with Zika virus. The virus, borne by infected Aedes aegypti mosquitos, is being linked to birth defects when pregnant women are bitten and infected. There are early reports also linking GBS to Zika infection, which could expose a wider range of infected people to the neuropathy. This summer infected Aedes mosquitos will likely reach southern portions of the United States, and travelers to countries where Aedes is endemic will increase. It is important to appreciate that the neurologic consequences of Zika virus are being actively investigated, and firm associations and consequences are yet to be established. Small fiber neuropathies are common and can be due to a number of underlying diseases, and a recent review also indicates that many are idiopathic. One cause is Sjögren syndrome, and a case series reviews clinical features. The diagnosis and underlying features of primary lateral sclerosis are a clinical challenge. Similarities between primary lateral sclerosis and hereditary spastic paraparesis (HSP) have long been noted. With a wide spectrum of gene mutations associated with HSP, clinical distinction between the 2 disorders is problematic. A review covers the wide spectrum of HSP. With no cure, the progre...
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Literature Review Source Type: research

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In this study, structural proteins of MERS-CoV were expressed in silkworm larvae and Bm5 cells for the development of vaccine candidates against MERS-CoV and diagnostic methods. The spike (S) protein of MERS-CoV lacking its transmembrane and cytoplasmic domains (SοTM) was secreted into the hemolymph of silkworm larvae using a bombyxin signal peptide and purified using affinity chromatography. The purified SοTM forms small nanoparticles as well as the full-length S protein and has the ability to bind human dipeptidyl peptidase 4 (DPP4), which is a receptor of MERS-CoV. These results indicate that bioactive S...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Jing Wang, Jia-Jia Du, Biao Jiang, Run-Zhen He, An-Xing LiAbstractShort-term feed deprivation or fasting is commonly experienced by aquaculture fish species and may be caused by seasonal variations, production strategies, or diseases. To assess the effects of fasting on the resistance of Nile tilapia to Streptococcus agalactiae infection, vaccinated and unvaccinated fish were fasted for zero, one, three, and seven days prior to infection. The cortisol levels of both vaccinated and unvaccinated fish first decreased and then increased ...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
ConclusionIn our study, the Met-allele was associated with higher stress levels. To the best of our knowledge, this is the first study investigating this area. The findings from this study should trigger more investigators to focus on the impact of stress, due to the potential effects of these genes, on medical students.
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
ConclusionsThis is the first randomised investigation of BP self-monitoring for the management of pregnancy hypertension and indicates that a large RCT would be feasible.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionsAlpha-synchronized rTMS of left DLPFC is feasible, safe and has specific single-session neuromodulatory effects in patients with antidepressant-resistant MDD. Future studies need to further elucidate the mechanisms, optimize the parameters and investigate the therapeutic potential and efficacy of brain oscillation-synchronized rTMS in MDD.
Source: Brain Stimulation - Category: Neurology Source Type: research
Publication date: Available online 12 October 2019Source: Journal of Hospital InfectionAuthor(s): Jaspreet Dhanda, James Gray, Ellen Knox, Amreen Bashir
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
In the original publication of this article [1], there are error in the Fig.  5, the “ml” should be replaced by “mL” (Fig. 5A) and “IFNγ” should be “IFN-γ” in Fig. 5A, B. The correct figure is below:
Source: Veterinary Research - Category: Veterinary Research Source Type: research
ConclusionOur study showed a significant association between alterations in intestinal microbial composition and T1D; however, in some articles, it is not clear which one happens first. Investigation of altered gut microbiota can help in the early detection of T1D before seropositivity. Targeted microbiome modulation can be a novel potential therapeutic strategy.
Source: Gut Pathogens - Category: Microbiology Source Type: research
João A. P. Coutinho It was recently shown that tetramethylammonium chloride presented negative deviations to ideality when mixed with tetraethylammonium chloride or tetrapropylammonium chloride, leading to a strong decrease of the melting points of these salt mixtures, in a behavior akin to that observed in the formation of deep eutectic solvents. To better rationalize this unexpected melting point depression between two structurally similar compounds devoid of dominant hydrogen bonding capability, new solid–liquid equilibria data for tetramethylammonium-based systems were measured and analyzed in this...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Tubal reversal and pregnancy are possible after endometrial ablation. Dr. Monteith offers hope to women who want to ahve a baby after endometrial ablation. The post Can You Get Pregnant After Endometrial Ablation And Tubal Ligation? appeared first on A Personal Choice.
Source: Tubal Reversal Blog - Category: Reproduction Medicine Authors: Tags: Endometrial Ablation Greencastle Pennsylvania Source Type: blogs
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