Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets
Conclusion These results show that platelets, which have a large repertoire of TLRs and IL-1 receptors, express high levels of IL-1R8, which plays a non-redundant function as a regulator of thrombocyte activity in vitro and in vivo.
Source: Cardiovascular Research - Category: Cardiology Authors: Anselmo, A., Riva, F., Gentile, S., Soldani, C., Barbagallo, M., Mazzon, C., Feruglio, F., Polentarutti, N., Somma, P., Carullo, P., Angelini, C., Bacci, M., Mendolicchio, G. L., Voza, A., Nebuloni, M., Mantovani, A., Garlanda, C. Tags: Vascular Biology Source Type: research
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