Sickle cell trait and health concerns in Army soldiers

Soldiers with sickle cell trait didn ’t have an elevated risk of death. They did have an increased risk, similar to older soldiers and some other groups, of a condition called exertional rhabdomyolysis.
Source: NIH Research Matters from the National Institutes of Health (NIH) - Category: Consumer Health News Source Type: news

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Discussion Potassium (K+) is an alkali metal (Group 1 of periodic table with Hydrogen, Lithium and Sodium) with an anatomic number of 19. Its chemical symbol K, comes from the medieval Latin, kalium which means potash (mainly potassium carbonate or potassium hydroxide), the substance it was first isolated from. Potassium is an important cation and it mainly resides in the intracellular fluid with only a small amount in the extracellular fluid. Potassium regulates cell volume, pH and enzyme functions. Hyperkalemia is defined as a potassium level> 5.5 mEq/L in children and> 6.0 mEq/L in newborns. Hyperkalemia incre...
Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Authors: Grigorian A, Gabriel V, Nguyen NT, Smith BR, Schubl S, Borazjani B, Joe V, Nahmias J Abstract PURPOSE: Obesity has been shown in a single-center study to be a risk factor for rhabdomyolysis. More recently, sickle cell trait, known to be more prevalent in blacks, has been shown to be a risk factor for rhabdomyolysis. We hypothesized that in trauma patients, black race and a higher body mass index (BMI) are associated with risk for rhabdomyolysis and acute kidney injury (AKI). MATERIALS AND METHODS: The National Trauma Data Bank (NTDB) was queried (2013-2015) to identify patients age ≥18 years an...
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
​BY GREGORY TAYLOR, DO, &JACKLYN M​CPARLANE, DO​A 33-year-old woman with a past medical history of sickle cell SS presented to the emergency department with chest pain, difficulty breathing, and a cough for two days. Her chest pain was diffuse, without radiation, and partially reproducible. Her cough was nonproductive, and she also reported fever and chills.The patient noted this was different from her normal back and leg pain from past sickle cell crises. She was following up with a sickle cell specialist, and was compliant with her hydroxyurea treatment.Her temperature was 102.8°F, blood pressure was 94/60 ...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
We present a case of exertional rhabdomyolysis in a mixed martial artist with sickle cell trait in order to illustrate the hazards of weight cutting and ensuing critical illness. Sickle cell trait is known to predispose patients to exertional rhabdomyolysis and multiple fatal cases have been reported in the setting of strenuous exercise. Dehydration and consequent electrolyte abnormalities make combat sport athletes with sickle cell trait particularly vulnerable to this entity. This case suggests a potential role for sickle cell trait screening in this population and underscores the need for safer weight-control practices ...
Source: International Journal of Sport Nutrition and Exercise Metabolism - Category: Sports Medicine Authors: Tags: Int J Sport Nutr Exerc Metab Source Type: research
CONCLUSIONS: ER is a serious complication of strenuous physical activity that can threaten renal function. ER tends to occur in August, which coincides with the start of football practice when athletes are more likely to be detrained. The condition can occur in Black athletes in the absence of sickle cell trait. ER carries a good prognosis when recognized early and treated adequately. PMID: 29855209 [PubMed - as supplied by publisher]
Source: The Physician and Sportsmedicine Online - Category: Sports Medicine Tags: Phys Sportsmed Source Type: research
No abstract available
Source: Neurology Today - Category: Neurology Tags: Features Source Type: research
Despite the fact that we categorize sickle cell disease as an autosomal-recessive trait, carriers of the sickle cell mutation might not remain clinically unaffected. The so-called sickle cell trait has been implicated in sudden death and in  exertional rhabdomyolysis, and some studies have measured a substantially increased risk of these outcomes in this population. What has been lacking is a thorough, longitudinal population-based study, a project that has now been completed by Nelson et al. The authors accessed data from the Stanfo rd Military Data Repository, a resource that includes all inpatient and outpatie...
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Tags: Editors ’ Corner Source Type: research
Sickle cell trait doesn’t raise the risk of death but does raise the risk of exertional rhabdomyolysis among black soldiers, “a population that is known to engage consistently in regular and...
Source: Hospitalist News - Category: Hospital Management Source Type: research
New England Journal of Medicine,Volume 375, Issue 5, Page 435-442, August 2016.
Source: New England Journal of Medicine - Category: Internal Medicine Authors: Source Type: research
CONTEXT: Sports medicine providers frequently return athletes to play after sports-related injuries and conditions. Many of these conditions have guidelines or medical evidence to guide the decision-making process. Occasionally, however, sports medicine pr...
Source: SafetyLit - Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
More News: Health | National Institutes of Health (NIH) | Rhabdomyolysis | Sickle Cell Anemia