Gene scanning 'could improve screening for oesophageal cancer'

Conclusion This prospective cohort study aimed to see whether a test performed on patients with non-cancerous Barrett's oesophagus may be able to predict whether the condition progressed to oesophageal cancer.  Overall, they found genetic diversity in the oesophageal cell samples at the start of the study seemed to be linked to the risk of cancer progression. However, the research has limitations to consider: By design, this study is only able to draw links – it does not propose treatment or lifestyle steps to be taken to reduce risk. The sample of patients in this study is small, so we cannot rule out that any associations seen are down to chance. The length of follow-up it not sufficiently long to see how many of the participants went on to develop cancer, as this can take 10 to 20 years. It is unclear whether the researchers have taken into account other risk factors for oesophageal cancer, such as smoking, drinking too much alcohol over a long period of time, being overweight or obese, and having an unhealthy diet. The future aim of such a test could be to reduce the need for regular monitoring in patients at low risk of going on to develop cancer. But more research is needed to confirm the use of such a test. The exact cause of oesophageal cancer is unknown, but stopping smoking, cutting down on alcohol, losing weight and having a healthy diet may all help reduce your risk. Links To The Headlines S...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Genetics/stem cells Source Type: news

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Publication date: Available online 20 July 2019Source: European UrologyAuthor(s): Elise De Bleser, Barbara Alicja Jereczek-Fossa, David Pasquier, Thomas Zilli, Nicholas Van As, Shankar Siva, Andrei Fodor, Piet Dirix, Alfonso Gomez-Iturriaga, Fabio Trippa, Beatrice Detti, Gianluca Ingrosso, Luca Triggiani, Alessio Bruni, Filippo Alongi, Dries Reynders, Gert De Meerleer, Alessia Surgo, Kaoutar Loukili, Raymond MiralbellAbstractBackgroundStereotactic body radiotherapy (SBRT) and elective nodal radiotherapy (ENRT) are being investigated as metastasis-directed treatments in oligorecurrent prostate cancer (PC); however, comparat...
Source: European Urology - Category: Urology & Nephrology Source Type: research
ConclusionWe performed cholecystectomy by using IFC to identify the aberrant subvesical bile duct. To the best of our knowledge, this is the first report showing the fluorescence image of an aberrant subvesical bile duct in a state of nature.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionA high index of suspicion, coupled with a tailored, multidisciplinary approach, is essential to achieve the best possible outcome. Conservative management may be worthwhile in a stable patient despite delayed presentation. Although TOE is considered a safe procedure, physicians should be made aware of such a dreaded complication.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 19 July 2019Source: International Journal of Surgery Case ReportsAuthor(s): Dario Iadicola, Massimo Branca, Massimo Lupo, Eugenia Maria Grutta, Stefano Mandalà, Gianfranco Cocorullo, Antonino MirabellaAbstractIntroductionTraumatic diaphragmatic injuries are rare complications resulting from a thoracic-abdominal blunt or penetrating trauma. Left-sided diaphragmatic injuries are more commonly reported in literature. Bilateral injuries are extremely rare, occurring in about 3% of the patients and just few cases reported in literature. Traumatic diaphragmatic hernias are definitely a m...
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThe incidence of midline and lateral port site recurrence after laparoscopy for diagnosis or resection of ovarian cancer has not been determined. Limitation of trochar sites to the midline may reduce the extent of abdominal wall disease spread.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThere is evidence that newborns have a much higher potential for wound healing than adults. Proper position in long-term immobilization of toes is important to prevent scar contracture and deformity.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionsPeritoneal tunnels in the inguinal region or at the porta hepatis should be opened by surgical dissection so that all foci of peritoneal metastases are removed at a complete cytoreductive surgery and these sites treated with chemotherapy.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThere is some previous caution in using a laparoscopic approach for cystic masses due to potential seeding intra-operatively, in case of fluid spillage of a possible malignant neoplasm. We show through our case that it is possible to efficiently and safely use such an approach.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionVariations in mesenchymal gastrointestinal tumors is vast, rendering diagnosis by radiology alone difficult. As such, characteristic histologic and immunostaining features are cornerstones in precise diagnosis of esophageal schwannomas. Despite being rare in incidence, symptomatic esophageal schwannoma lesions can be excised entirely, with low rate of recurrence and favorable overall outcomes.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionsPrevention of recurrent right colon cancer is an import consideration for primary resection. However, if this duodenum is involved by recurrence, techniques for resection exist.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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