Local control dependence on consecutive vs. nonconsecutive fractionation in lung stereotactic body radiation therapy.

CONCLUSION: Five-fraction SBRT delivered over non-consecutive days imparts superior LC and similar toxicity compared to consecutive fractionation. These results should be validated in independent datasets and in a prospective fashion. PMID: 27543255 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research

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Conditions:   Metastatic Lung Non-Small Cell Carcinoma;   Refractory Lung Non-Small Cell Carcinoma;   Stage III Lung Cancer AJCC v8;   Stage IIIA Lung Cancer AJCC v8;   Stage IIIB Lung Cancer AJCC v8;   Stage IIIC Lung Cancer AJCC v8;   Stage IV Lung Cancer AJCC v8;   U nresectable Lung Non-Small Cell Carcinoma Interventions:   Drug: Atezolizumab 1200 MG in 20 ML ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsThis first report of SBRT for pulmonary LCNEC demonstrates that SBRT is a feasible modality for this rare disease. A multidisciplinary thoracic oncology approach involving medical oncology, thoracic surgery, radiation oncology and pulmonology is strongly recommended to ensure proper patient selection for receipt of SBRT.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: Salvage SBRT for isolated local failures after initial SBRT appears safe, with low treatment-related toxicity and encouraging rates of tumor control. PMID: 31481272 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
Stereotactic body radiotherapy (SBRT) is an established treatment option in the management of patients with early-stage non-small cell lung cancer (NSCLC). Prospective studies have demonstrated that SBRT achieves high rates of local tumor control [1 –3]. Compared to conventionally-fractionated radiotherapy (CFRT) for early stage NSCLC, SBRT is associated with equivalent tumor control, shortened treatment times, and decreased toxicity, with larger retrospective studies even suggesting a survival benefit [4–7].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
Conditions:   Lung Non-Small Cell Carcinoma;   Positive Surgical Margin;   Resected Mass;   Stage III Lung Cancer AJCC v8;   Stage IIIA Lung Cancer AJCC v8;   Stage IIIB Lung Cancer AJCC v8;   Stage IIIC Lung Cancer AJCC v8;   Stage IV Lung Cancer AJCC v8;   Stage IVA  Lung Cancer AJCC v8;   Stage IVB Lung Cancer AJCC v8 Interventions:   Other: Quality-of-Life&nb...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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