How To Find Your Calling (From 5 People Who Found Theirs)

Why does our culture perpetuate the belief that “finding oneself” is an age-specific phase, reserved only for angst-ridden teenagers and wanderlust-stricken 20-somethings? The notion of finding a passion is all-too-frequently aligned with youth and impulsivity, but truthfully, we’re all quietly seeking our next challenge, our next calling. We’re of the belief that it’s never too late to course correct your life, and given the job-hopping numbers, we’re probably not the only ones. Though the U.S. Bureau of Labor Statistics does not regularly track career changes, in a recent study of late-period baby boomers it found that people will hold an average of 11 different jobs throughout their lifetime, and for some, as many as 15 jobs. (For younger Americans, that number will likely be much higher.) To help you take that eager leap, we’ve partnered with Chevrolet Malibu to bring you these courage-inducing tips for finding your passion, from five people who found theirs. 1.  When Jim Stevens suddenly and unexpectedly lost his vision in 1993, he believed his days as an artist were over. A stroke in his visual cortex ― brought on by bullet fragments that had been there since 1970, when he was shot serving as a U.S. Army sergeant during combat in Vietnam ― rendered him legally blind, except for a small pinhole of vision in both eyes. In the wake of the loss of his teaching job at the University of Colorado in Denver, paired with a sep...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Fahd M. Abdelkarem, Ezz-Eldin K. Desoky, Alaa M. Nafady, Ahmed E. Allam, Aldoushy Mahdy, Maki Nagata, Tomofumi Miyamoto, Kuniyoshi ShimizuAbstractFurther chemical study of the crude extract of the soft coral Heteroxenia fuscescens (Fam., Xeniidea), led to isolation of two new sterols, Heterofuscesterols A (1) and B (2), a sterol isolated for the first time from natural sources, 3β,5α,6β-trihydroxyandrosta-17-one (3), along with one new hydroperoxy sesquiterpene, Heterofusceterpene A (4), and one known ceramide (5). Their structu...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Publication date: Available online 21 February 2020Source: Chemical Engineering JournalAuthor(s): Meitong Ou, Chao Pan, Yongkang Yu, Xuan Wang, Yun Zhou, Hanjie Zhang, Qinzhen Cheng, Meiying Wu, Xiaoyuan Ji, Lin MeiAbstractExcessive reactive oxygen species (ROS), as effective cancer therapeutic agents, can promote tumor apoptosis. However, the clinical applications of ROS-mediated cancer therapies still have many limitations, such as self-defects of traditional photosensitizer, adverse tumor microenvironment (TME), and insufficient ROS production. Here, two-dimensional and highly oxidized ilmenite nanosheets (HOIL NSs, for...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: Available online 21 February 2020Source: Chemical Engineering JournalAuthor(s): Yang Zhang, Yanjun Xu, Di Sun, Zheying Meng, Weiwei Ying, Wei Gao, Rui Hou, Yuanyi Zheng, Xiaojun Cai, Bing Hu, Xianfang LinAbstractAs a promising treatment modality with spatial and temporal control, alternating magnetic field (AMF) triggered magnetic hyperthermal therapy (MHT) shows broad and promising applications to overcome the drawbacks of traditional focal therapies in combating cancer. However, the MHT efficacy is still not satisfactory with the presence of heat shock proteins (HSPs). In addition, sustained tumor hypox...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/D0CC00416B, CommunicationXinwei Tian, Zhao Li, Ning Ding, Jiahang Zhang We have developed a novel near-infrared ratiometric fluorescent theranostic nanoprobe. Reaction with glutathione, it would release a near-infrared fluorophore and chemotherapy drug. Notably, this nanoprobe can selectively kill cancer HeLa,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
ABSTRACT: Objectives: To estimate the magnitude of gender differences in disability among adults aged 60 and older and to evaluate whether they can be associated with social gender inequality and socioeconomic contextual factors at the level of Brazilian federative units. Methods: This is a multilevel study that used data from 23,575 older adults of 27 federative units who participated in the 2013 Brazilian Health Survey. The activity limitation index was developed from the item response theory, using activities of daily living and instrumental activities of daily living variables. The association of individual and context...
Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
This article presents her outstanding character and most important lines of research. The focus of her studies covered alkylative and oxidative damage to DNA bases, in particular mutagenic and carcinogenic properties of purines with an open imidazole ring and 8-oxo-7,8-dihydroguanine (8-oxoGua). They also included analysis of mutagenic properties and pathways for the repair of DNA adducts of lipid peroxidation (LPO) products arising in large quantities during inflammation. Professor Tudek did all of this in the hope of deciphering the mechanisms of DNA damage removal, in particular by the base excision repair (BER) pathway...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
ConclusionsBlood Metallothionein- 2A relative expression and oxidant status may have a prognostic value in breast cancer patients.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
ConclusionOrganisational factors of safety climate, disability management and labour management processes appear to be associated with work injury and location of work within this workplace. The role of organisational factors should be considered in future studies examining interventions aimed at addressing work injury.
Source: Safety Science - Category: Occupational Health Source Type: research
Authors: Gok M, Sozuer E, Topal U, Akyuz M, Bozkurt GK, Hamurcu M, Deniz K Abstract Appendix vermiformis agenesis is quite rare. It is seen in 1/100,000 of patients who underwent laparotomy with an initial diagnosis of appendicitis. A 72-year-old woman who had not undergone any previous surgery was operated on for mechanical intestinal obstruction. Right hemicolectomy was performed due to obstructive tumoral mass in the hepatic flexure. There was no appendix vermiformis in exploration. Before deciding on the diagnosis of appendix agenesis, a thorough and rigorous exploration should be performed in ileocecal region ...
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Publication date: Available online 21 February 2020Source: Urology Case ReportsAuthor(s): Leila Haghighi, Mohsen Akbaribazm, Zahra Arab-Mazar, Mohsen RahimiAbstractHematobium species of this parasite tends to bladder and mesenteric arteries and it causes lesions in the bladder wall, urethra, and renal tubes. A 25-year-old man living in Tehran (a non-endemic and very rare area for schistosoma) suffers from symptoms such as hematuria with suprapubic pain, dysuria, fever, nausea and vomiting. Urine analysis showed a lot of red blood cells, after using cystoscopy of the area and receiving a bladder biopsy, a definitive diagnos...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
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