Role of MRP-1 and GST-Pi in MDR and their inhibition by indomethacin in AML

Conclusion MRP-1 is not likely to contribute to MDR, while GST-Pi might have a role in MDR phenotype in AML patients. Furthermore, GST-Pi inhibition significantly reduced MDR in AML patients.
Source: Alexandria Journal of Medicine - Category: Journals (General) Source Type: research