The accuracy of extracted target motion trajectories in four-dimensional cone-beam computed tomography for lung cancer patients.
CONCLUSIONS: This study showed the magnitude of underestimation toward the inferior direction of target motion in clinical 4D-CBCT. PMID: 27528116 [PubMed - as supplied by publisher]
Cancer survival rates for esophagus, stomach, colon, rectum, pancreas, lung,...Read more on AuntMinnie.comRelated Reading: AI predicts lung cancer survival from CT scan data Lancet: Cancer survival rates improve but vary widely Cancer deaths continue to fall, but CT lung screening lags ACS: U.S. cancer death rates continue to fall NEJM: Treatment, not screening, cuts breast cancer deaths
ConclusionIn a clinical setting, the new SiPM-based PET/CT system with a new BSREM reconstruction algorithm provided a higher SUVmax for suspected lymph node metastases compared to the PM-based system. However, no improvement in lung cancer detection was seen.
In a patient who had been diagnosed of located squamous cell lung carcinoma, pneumonectomy and adjuvant chemotherapy were performed. Brain recurrence and subsequent lung metastatic disease were uncontrolled by neurosurgery, holocranial radiotherapy and first-line chemotherapy. In August 2015, appearance of leptomeningeal carcinomatosis triggered severe clinical deterioration and threatened the patient's life. Anti-PD1 immune checkpoint inhibitor Nivolumab was initiated in an attempt to stop tumour growth, achieving a spectacular brain and pulmonary complete response and clinical improvement, without serious adverse effects...
About 77 percent of patients who received CT scans for lung cancer were diagnosed with cardiovascular disease, emphysema or osteoporosis, according to a new study showing the same scan can screen for additional diseases.
The authors regret they failed to note that the treatment period for patients included in this report occurred between 2000 and 2010 and not through the stated 2015 end date. The findings described, then, do not represent final data (including total numbers of patients and results) or conclusions for patients treated after 2010. Complete study data remain at the University of Maryland School of Medicine.
Restaging computed tomography scans of the chest/abdomen/pelvis are needed to assess extracranial disease burden and determine whether there is an accessible lesion for biopsy (if systemic therapy will be considered).1 Furthermore, this serves to rule out the potential of another primary that may warrant whole-brain radiation therapy consideration (ie, small cell lung cancer).
Conclusion: This first-in-human study demonstrates that 99mTc-labeled anti–PD-L1-single-domain antibody SPECT/CT imaging is safe and associated with acceptable dosimetry. Tumor uptake is readily visible against background tissues, particularly at 2 h when the T:BP ratio correlates with PD-L1 immunohistochemistry results.
CONCLUSION: a single sectional cross at the level of C3 can be used for the diagnosis of pre-sarcopenia. This new method avoids unnecessary irradiation, saves hospital costs and detects malnutrition before starting radiotherapy treatment in cancer patients who have lack of CT abdominal imaging. PMID: 31475837 [PubMed - as supplied by publisher]
Publication date: Available online 31 August 2019Source: The Annals of Thoracic SurgeryAuthor(s): Eric M. Robinson, Ilkka K. Ilonen, Kay See Tan, Andrew J. Plodkowski, Matthew Bott, Manjit S. Bains, Prasad S. Adusumilli, Bernard J. Park, Valerie W. Rusch, David R. Jones, James HuangABSTRACTBackgroundThere has been growing interest in limited resection and nonsurgical treatment for small lung cancers. Our objective was to examine the pattern and rate of occult N1 nodal metastasis in patients with peripheral, small (≤2 cm), clinically node-negative non-small cell lung cancer (NSCLC).MethodsPatients with peripheral
ConclusionSoftware-assisted 4D dynamic-ventilation CT can be considered as a novel imaging approach for accurate preoperative analysis of pleural invasion/adhesion of peripheral lung cancer.Key Points•4D dynamic-ventilation CT can correctly assess parietal pleural invasion/adhesion of peripheral lung cancer.•A unique color map clearly demonstrates parietal pleural invasion/adhesion.•Our technique can be expanded to diagnose “benign” pleural adhesions for safer thoracoscopic surgery.