Women's cancer risk may increase the longer they're obese

Conclusion This study adds to evidence that being overweight or obese for long periods of time may increase the risk of certain cancers, just as it increases the risk of cardiovascular disease and diabetes. The study's size and use of BMI measurements over time mean it is likely to be more reliable than smaller studies, or those that look at BMI only at one time point. The design allows researchers to look at how weight during a lifetime, rather than at one single point in life, may affect cancer risk. However, there are limitations. It's an observational study, so while researchers took account of known confounding factors such as smoking and exercise, it's always possible some factors were not accounted for. This means the study cannot prove that overweight directly caused cancer. The other main concern is that it relied on women remembering and correctly reporting their weight decades earlier, at ages 18 and 35. These caveats aside, the study is a serious attempt to quantify the risk that overweight and obesity contribute to cancer risk. Obesity levels have been rising in recent decades and figures from Public Health England show 65% of men and 58% of women in England were overweight or obese in 2014. The best way to keep to a healthy weight throughout life is to eat a healthy, balanced diet and take plenty of exercise. Some people struggle with their weight more than others, and it can be hard to shift weight once you've put it on. If you're worried about your weight ...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Obesity Source Type: news

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TYPE 2 diabetes can be managed by cutting down on highly calorific and sugary foods, but adding certain ingredients to your diet can also help. These two popular cooking ingredients could help to lower blood sugar and control diabetes symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 18 January 2019Source: Biosensors and BioelectronicsAuthor(s): Ya Cao, Yuhao Dai, Hong Chen, Yingying Tang, Xu Chen, Ying Wang, Jing Zhao, Xiaoli ZhuAbstractIn this work, DNA-templated silver nanoclusters (DNA-AgNCs) with unique fluorescent and electrochemical properties are prepared as dual signal probes for both qualitative imaging and quantitative detection of cancer cells in an integrated system. ITO electrode that has good light transmittance and electric conductivity is employed as a substrate for dual analysis of cancer cells. ITO electrode is firstly modified by AS1141 aptamer, wh...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
CONCLUSION: Preventive use of carvedilol in patients undergoing anthracycline-based chemotherapy may be associated with a reduced incidence of LVSD, higher LVEF value, better diastolic function, and lower troponin I level. RCTs with larger sample size and longer follow-up are needed to verify these findings. PMID: 30656389 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Authors: Stopp T, Falcone V, Feichtinger M, Göbl C Abstract Bariatric surgery is recommended when other weight loss interventions, such as lifestyle modification or medications, have failed. A considerable number of women undergoing bariatric surgery are of childbearing age; hence, it is necessary to be aware of the effects of bariatric surgery on pregnancy for managing these patients. Although bariatric surgery is associated with positive effects on cardiovascular and metabolic parameters, side effects such as anaemia, the risk of developing internal hernia, altered glucose metabolism and the risk of small fo...
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey. J Plast Surg Hand Surg. 2019 Jan 18;:1-6 Authors: Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA Abstract Autologous breast reconstruction (BR) aims to restore body image and improve health-related quality of life in women undergoing mastectomy due to breast cancer. We wanted to explore patient-reported cosmetic results and satisfaction 10 or more years post BR surgery, using deep inferior epigastric perforator flap (DIEP). This i...
Source: Journal of Plastic Surgery and Hand Surgery - Category: Surgery Tags: J Plast Surg Hand Surg Source Type: research
Authors: Hurst Z, Liyanarachchi S, He H, Brock P, Sipos JA, Nabhan F, Kebebew E, Green P, Cote GJ, Sherman SI, Walker CJ, Chang YS, Xue S, Hollingsworth B, Li W, Genutis L, Menq E, de la Chapelle A, Jhiang SM Abstract BACKGROUND: Thyroid cancer patients with radioiodine refractory (RAI-R) disease, resulting from insufficient RAI delivery and/or RAI resistance, have increased mortality and limited treatment options. To date, studies have largely focused on tumor mutations associated with different stages of disease, which could provide prognostic value for RAI-R disease. We hypothesize that germline variants contrib...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
CONCLUSIONS: Strategies that reduce the uptake of smoking and encourage current smokers to quit could substantially reduce the future incidence of pancreatic cancer in Australia, particularly among men. PMID: 30656698 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
CONCLUSIONS: The 2013 PCE-ASCVD or 1991 Framingham should be used as CVD risk models in Australian. However, the CVD high risk threshold for initiating CVD primary preventive therapy requires reconsideration. PMID: 30656697 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Authors: Adie S, Harris I, Chuan A, Lewis P, Naylor JM Abstract The minimum requirements for total knee arthroplasty (TKA) are significant, prolonged symptoms with supporting clinical and radiological signs. Despite interest in screening tools, there is limited evidence for a specific symptom threshold that justifies surgery. Non-operative treatments including medications, exercise and weight loss are unlikely to reverse radiographic changes, but they may improve symptoms and delay the need for surgery. Many patient factors such as mental health and obesity affect both the level of symptomatic improvement after sur...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Authors: Titmuss A, Davis EA, Brown A, Maple-Brown LJ PMID: 30656687 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
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