Clinical Implications of CD30 Expression in Aggressive B-Cell Lymphomas.
CONCLUSION: Expression of CD30 in patients with both DLBCL and other aggressive B-cell lymphomas and the absence of MYC oncogene-driven proliferation in the majority of these tumors suggests that brentuximab may be a particularly effective form of targeted therapy in the subset of patients with high CD30 expression.
PMID: 27521276 [PubMed - in process]
Source: Clinical Lymphoma and Myeloma - Category: Cancer & Oncology Authors: Malysz J, Erdman P, Klapper J, Zhu J, Creer M, Bayerl MG Tags: Clin Lymphoma Myeloma Leuk Source Type: research