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Antioxidant Activity and Chemical Characterization of Extracts from the Genus Hymenaea

Conclusion: These results suggest that H. courbaril should be further explored with a focus on use in cosmetic, pharmaceutical and food formulations.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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DiscussionThe systematic review builds on a previous scoping review in this field and expands upon this by synthesising data on both product technical characteristics and design features. The review will be of particular value to stakeholders engaged in diagnostic procurement and manufacturers interested in developing cholera or diarrheal disease diagnostics.Systematic review registrationPROSPEROCRD42016048428.
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Chagas disease is included in the neglected tropical diseases list and is endemic to 21 Latin American countries. The two drugs currently available for treating Chagas disease are nifurtimox and benznidazole and both result in many significant side effects. The study describes the synthesis and biological evaluation of 3,5-disubstituted isoxazoles. Isoxazoles were obtained by reaction of flavones and hydroxylamine and either alkylated at the free hydroxyl group and/or nitrated at the isoxazole ring. These compounds were evaluated for their in vitro anti-Trypanosoma cruzi activity against trypomastigote and amastigote forms...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
Abstract International trade in live plant materials has increased worldwide over the last four decades. This has led to a dramatic increase in the introduction, establishment and spread of non‐native plant pathogens. Regulatory authorities need advice on measures that may mitigate these adverse consequences of trade. Risk models may be used to underpin such advice. In this review, we give a systematic overview of the data needed for a quantitative risk model for Phomopsis vaccinii, which causes stem and fruit infections on Vaccinium species, and sometimes death, potentially also on native wild Vaccinium species in the E...
Source: Annals of Applied Biology - Category: Biology Authors: Tags: REVIEW ARTICLE Source Type: research
ConclusionOur experience further highlights the challenges of LTBI screening prior to LT and suggests that QFT may be a poor predictor of active TB in higher risk pre‐transplant populations. Candidates should be screened as early as possible to optimize QFT performance, and local epidemiological data should be used to create institution‐specific screening protocols in areas with large populations from TB‐endemic regions. Management should consider TB risk factors, QFT, and imaging instead of reliance on QFT testing alone.
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
Publication date: June 2018 Source:Nonlinear Analysis: Real World Applications, Volume 41 Author(s): Yachun Tong, Chengxia Lei This paper concerns an SIS epidemic reaction–diffusion model, which includes the possibility for spontaneous infection, in addition to disease transmission. We prove the global asymptotic stability of the unique endemic equilibrium when the spatial environment is homogeneous. When the spatial environment is heterogeneous, we show the existence of endemic equilibria and then analyze their asymptotic profile if the movement (migration) rate of the susceptible or infected population is small or...
Source: Nonlinear Analysis: Real World Applications - Category: Research Source Type: research
AbstractPurpose of ReviewSyphilis continues to cause morbidity and mortality worldwide. While syphilis infection is easily identifiable and treatable, rates of syphilis infection continue to increase among select populations in high-income countries and remain at endemic levels in low- and middle-income countries.Recent FindingsWorld Health Organization recommended strategies have led to the dual elimination of mother-to-child transmission of syphilis and HIV in several countries; however, outbreaks among select populations need to be adequately addressed.SummaryContinued vigilance and investment are needed to address syph...
Source: Current Epidemiology Reports - Category: Epidemiology Source Type: research
We report a case of imported pulmonary coccidioidomycosis caused by Coccidioides posadasii in a patient who was misdiagnosed as tuberculosis and mistreated with antituberculosis medications for 18 months. The symptoms were not relieved until antifungal treatment was started. An extensive review of the coccidioidomycosis cases occurring in China reveals 38 cases, 16 of which had no associated history of travel to any traditional endemic areas. We speculate that some factors may drive Coccidioides spp. transference to China, which then causes those domestic infections. Moreover, we indicate the first, to the best of our...
Source: Mycoses - Category: Research Authors: Tags: SINGLE CASE REPORT Source Type: research
Abstract Leishmaniasis is a worldwide tropical infectious disease caused by different species of intracellular protozoa parasites of the genus Leishmania . Herein, we report a 78-year-old man with unusual diffuse cutaneous leishmaniasis (DCL) who had a history of opium abuse and chronic obstructive pulmonary disease (COPD). He had multiple papular, crusted and severely ulcerated lesions extended to his arm and chest. Direct smears and skin punch biopsy of the lesions were suggestive of leishmaniasis. Parasite DNA was amplified from ulcers, and identified as Leishmania major by PCR-RFLP, confirmed by sequencing ana...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
This study describes the histopathological characteristics found in the skin lesions of patients with CL caused by Leishmania (V.) panamensis in Panama. We analyzed 49 skin biopsy samples from patients with clinical suspicion of CL, by molecular tests (PCR for subgenus Viannia and HSP-70) and by Hematoxylin-Eosin staining. Samples were characterized at the species level by PCR-HSP-70/RFLP. From the 49 samples studied, 46 (94%) were positive by PCR and were characterized as Leishmania (V.) panamensis. Of these, 48% were positive by Hematoxylin-Eosin staining with alterations being observed both, in the epidermis (85%) and i...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Authors: Cesinaro AM, Nosseir S, Mataca E, Mengoli MC, Cavatorta C, Gennari W Abstract Canine Leishmaniasis is a disease endemic in many parts of Europe, carried by insects of phlebotomous species. Humans are occasional hosts of the parasites. Cases of human leishmaniasis have been registered in Italy, particularly in the southern and coastal regions. In the period 1997-2016, we collected a series of 35 patients affected by cutaneous leishmaniasis, uncovered by skin biopsy and histological examination, 21 of them found in last 3 years. The patients, 28 males and 7 female, aged between 19 and 91, resided in a restri...
Source: Pathologica - Category: Pathology Tags: Pathologica Source Type: research
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