Procedure-Related Complications and Survival Following Fetoscopic Endotracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia: Systematic Review and Meta-Analysis in the FETO Era

This study aims to assess the procedure-related complications and survival following fetoscopic endotracheal occlusion (FETO) for severe congenital diaphragmatic hernia. Materials and Methods A systematic review and meta-analysis of PubMed and Scopus database searching for FETO procedure in severe CDH (lung-to-head ratio [LHR] 
Source: European Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Review Article Source Type: research

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CONCLUSION: Morgagni hernias are amenable to minimally invasive repair with this simple technique. With large defects, synthetic patches should be used. Recurrences are rare, and morbidity is low. PMID: 31926567 [PubMed - in process]
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
We report a case of Fryns Syndrome who was incidentally found to have Edward Syndrome as well. Such an extremely rare combination is yet to be reported in medical literature.Also with updated genetic studies, better diagnostics and treatment options coming up in future, there are chances to improve the survivability of these babies. It is prudent to document all such cases to aid in better understanding of the disease process.
Source: Medical Journal Armed Forces India - Category: General Medicine Source Type: research
To determine: 1) the prevalence of persistent pulmonary hypertension (PPH) and its impact on postnatal outcome in infants with congenital diaphragmatic hernia (CDH) undergoing standardized management; 2) correlations between pre- and postnatal indicators and the presence of (refractory) PPH early in life.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session III Source Type: research
Congenital Diaphragmatic Hernia (CDH) associated with Omphalocele is a rare condition, and only a few case reports are available in the literature. Both conditions are associated with some degree of pulmonary hypoplasia. We hypothesize that the combination of CDH with Omphalocele might be associated with poorer outcomes.
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
The aim of this study was to evaluate our prenatal risk stratification system for risk-adjusted management in fetuses with isolated congenital diaphragmatic hernia (CDH).
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
CONCLUSIONS: The survival of infants with CDH is low, and PPHN is an important predictor of mortality. PMID: 31884435 [PubMed - in process]
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
This study was the first to show that the miR-130a-5p/Foxa2 axis played a crucial role in CDH-associated pulmonary hypoplasia. These findings may provide relevant insights into the prenatal diagnosis and prenatal therapy of CDH.
Source: Life Sciences - Category: Biology Source Type: research
We describe a newborn with fetal aberrant ductus venosus with progressive right ventricular dilation prompting early delivery. Post-natally, the baby had frequent episodes of cyanosis. Echocardiogram during distress showed compression of the inferior vena cava and of the right heart, with significant right to left shunt through patent foramen ovale. Infant underwent successful laparoscopic diaphragmatic hernia repair with resolution in her episodes of cyanosis.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Prenatal risk assessment of congenital diaphragmatic hernia (CDH) relies on prenatal ultrasound (U/S) and fetal magnetic resonance imaging (MRI). When the modalities differ in prognosis, it is unclear which is more reliable.
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
Congenital diaphragmatic hernia (CDH) is a complex disease that causes severe hypoxemic respiratory failure and significant morbidity and mortality.1 In the most severe cases, CDH is characterized by lung hypoplasia, severe pulmonary hypertension (PH), and cardiac dysfunction.2 Despite many advances in therapeutic options for CDH, the related PH and poor cardiac function often remain refractory to medical interventions, such as inhaled nitric oxide (iNO) therapy, and persist as the most common indications for extracorporeal membrane oxygenation therapy (ECMO) in the newborn period.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Editorials Source Type: research
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