Nuclear receptors as pharmacological targets, where are we now?
Nuclear receptors as pharmacological targets, where are we now?
Cell Mol Life Sci. 2016 Aug 9;
Authors: Volle DH
Abstract
Knowledge of integrative physiology is a major challenge for scientists, as even small deregulation could lead to diseases. Cells communicate with each other to control many processes such as growth, migration, survival, or differentiation. Such interaction could be achieved via several mechanisms either through cell-cell interactions and/or through the signaling of molecules that bind to receptors on the membrane or in the target cells. The produced molecules could have either autocrine, paracrine stimulations, or even act on distant organs (endocrine signaling).
PMID: 27506618 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Volle DH Tags: Cell Mol Life Sci Source Type: research
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