Botulinum Toxin Type A Inhibits α-Smooth Muscle Actin and Myosin II Expression in Fibroblasts Derived From Scar Contracture

This study aimed to explore the effect of BTXA on α-SMA and myosin II expression in fibroblasts derived from SC and to elucidate its actual mechanism further. Methods: Fibroblasts were isolated from tissue specimens of SC. Fibroblasts were cultured in Dulbecco modified Eagle medium with different concentrations of BTXA and their proliferation was analyzed through the tetrazolium-based colorimetric method at 1, 4, and 7 days. Proteins of α-SMA and myosin II were checked using Western blot in fibroblasts treated with different concentrations of BTXA at 1, 4, and 7 days. Results: Fibroblasts without BTXA treatment had a higher proliferation than that in other groups, which indicated that the proliferation of fibroblasts was significantly inhibited by BTXA (P
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Research Source Type: research

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By DAVE LEVIN, MD The 2019 Health 2.0 conference just wrapped up after several days of compelling presentations, panels, and networking. As in the past, attendees were a cross section of the industry: providers, payers, health IT (HIT) companies, investors, and others who are passionate about innovation in healthcare. Tech-enabled Services One of the more refreshing themes of the conference was an emphasis on how health IT can enable the delivery of services. This is a welcome perspective as too often organizations believe that simply deploying technology will solve their problems. In my 30+ years in healthcare, I...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Data Health 2.0 Health Tech Health Technology Start-Ups Burnout Datica Dave Levin health innovation Health IT tech-enabled services Source Type: blogs
It may be one of the country ’s hottest new industries, but setting up a medical cannabis business in Florida comes with sky-high barriers of entry that exclude all but the most well-funded entrepreneurs.
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Professor Alistair Burns' comments come as the opening ceremony and first match of the 2019 Rugby World Cup kicks off, with nations across the globe competing to win the Webb Ellis Cup.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
New technique could help authorities conduct triage in multiple-blaze scenarios More at This is a Research News item.
Source: NSF Discoveries - Category: Science Source Type: research
Publication date: Available online 18 September 2019Source: Arthroscopy TechniquesAuthor(s): Justin Hallock, Larry D. FieldAbstractThe formation of heterotopic ossification around the shoulder is a rare but potentially debilitating condition. It is found most commonly around the hip and is usually associated with an inciting event such as trauma, burn, previous surgery, or traumatic brain/spinal cord injury. The formation of shoulder heterotopic ossification following arthroscopic surgery is very uncommon, with few data pertaining to it in the current literature. Formation of heterotopic ossification in the shoulder after ...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
You shouldn ’t feel ashamed for feeling suicidal. Here’s how you can push back.I saw a news item a few months ago that troubled me.[1] At first, the item was in regard to a K-pop idol (Goo Hara) who my third oldest daughter and I enjoyed watching and listening to in the group, KARA. During KARA’s heyday, my daughter and I followed all their videos and song releases. It was fun —at least until she discovered a guy who had his own rock band. Then dad and K-pop were replaced with an electric guitar and a husband. Poor Daddy.Reading about anybody’s suicide attempt is heartbreaking, but Goo’s...
Source: The Splintered Mind by Douglas Cootey - Category: Psychiatry Tags: Depression Family Goodreads Suicide Source Type: blogs
In the Scheetz household, back-to-school anxiety reached new heights this fall. Jami Scheetz’s 15-year-old son Devon, who has severe asthma, kicked a brutal vaping habit over the summer, with help from a nicotine patch. But as soon as school started and he was once again around kids vaping, his habit returned. On Sept. 12, Devon vaped at school and immediately began sweating and vomiting. Though Scheetz, who lives in Sellersville, Pa., says her son is now fine, she can’t shake thoughts of kids who have been hospitalized or died after using e-cigarettes. “Vaping scares me more [than smoking], because they ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized vaping Source Type: news
Title: Chemicals From Heat-Not-Burn Tobacco Devices Not Harmless: StudyCategory: Health NewsCreated: 9/18/2019 12:00:00 AMLast Editorial Review: 9/19/2019 12:00:00 AM
Source: MedicineNet Lungs General - Category: Respiratory Medicine Source Type: news
Allogeneic hematopoietic cell transplantation involves consideration of both donor and recipient characteristics to guide the selection of a suitable graft. Sufficient high-resolution donor–recipient HLA match is of primary importance in transplantation with adult unrelated donors, using conventional graft-versus-host disease prophylaxis. In cord blood transplantation, optimal unit selection requires consideration of unit quality, cell dose and HLA-match. In this summary, the National Marrow Donor Program (NMDP) and the Center for International Blood and Marrow Transplant Research, jointly with the NMDP Histocompatib...
Source: Blood - Category: Hematology Authors: Tags: Special Reports, Transplantation, Free Research Articles, CME article Source Type: research
Many people believe that dark skin is not susceptible to sun damage. This is not true. Although darker skin tones are less likely to burn, people of all skin tones can get sunburn or skin cancer. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Dermatology Source Type: news
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