Frozen Embryos May Increase Chances Of Becoming Pregnant

BOSTON (CBS) – Fertility experts usually prefer to work with fresh embryos when women are undergoing in vitro fertilization (IVF), but according to a new study frozen may be better than fresh in some women. About 10% of women of reproductive age have polycystic ovarian syndrome (PCOS). It’s a common cause of infertility and IVF in these women can pose some risks. But researchers looked at more than 1500 women with PCOS and found that those who received frozen embryos had lower rates of complication and a greater likelihood of a successful pregnancy than those who received fresh embryos. The scientists say fertility specialists should consider freezing all embryos women with PCOS before transferring them into the womb.
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local News Syndicated Local CBS Boston Dr. Mallika Marshall In Vitro Fertilization Source Type: news

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Vitamin D deficiency in women diagnosed with polycystic ovary syndrome (PCOS) remarkably decreases the chance of pregnancy, which might be related to its impact on metabolic abnormalities in these patients. It...
Source: Reproductive Biology and Endocrinology - Category: Endocrinology Authors: Tags: Research Source Type: research
CONCLUSION: Overall, the findings of this trial supported that 50,000 IU vitamin D supplementation every other week for 8 weeks had beneficial effects on insulin metabolism, and lipid profile of infertile women with PCOS who are candidate for IVF. These benefits might not be evident upon having sufficient vitamin D levels. TRIAL REGISTRATION: This study was retrospectively registered in the Iranian website ( ) for clinical trials registration ( : IRCT20170513033941N27). PMID: 30286768 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
CONCLUSION: In summary, Th1 and Th17 bias and reduction of Treg and Th2 cells as regulators of immune responses might be involved in the pathogenesis of PCOS. These results are suggestive of an altered immune response to inflammatory status in PCOS patients, likely causing some complications such as infertility in these patients. PMID: 30246693 [PubMed - in process]
Source: Iranian Journal of Immunology - Category: Allergy & Immunology Tags: Iran J Immunol Source Type: research
Publication date: Available online 13 September 2018Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Tabibnejad N., Soleimani M., A. AflatoonianAbstractObjectivesOocyte parameters as well as embryo developmental kinetics can be applied as non-invasive predictors for selection of viable embryos and clinical outcomes. Time-lapse morphokinetic events in conjunction with zona pellucida birefringence (ZPB) and meiotic spindle visualization (MSV) have been evaluated for predicting pregnancy outcome.Study designWe assessed a total of 547 embryos from 100 intra cytoplasmic sperm injection c...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Abstract BACKGROUND: Letrozole is widely employed as ovulation induction agent in women with PCOS, but its use in mild stimulation (MS) protocols for IVF is limited. Aim of the present study was to evaluate the feasibility of a MS protocol with letrozole plus hMG in non-obese PCOS women undergoing IVF after a metformin pre-treatment. METHODS: We retrospectively evaluated the data of 125 non-obese PCOS undergoing MS with letrozole plus hMG, 150 IU as starting dose, (group 1, N = 80) compared to those undergoing a conventional IVF stimulation protocols (CS) (group 2, N = 45) pri...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
ni ME Abstract Context: There is increasing evidence for MIS/AMH physiologic activity in the human uterus, so it is relevant to study how MIS/AMH levels impact pregnancy. Objective: To investigate the association of MIS/AMH levels with risk of adverse obstetric outcomes. Design: Retrospective cohort study. Setting: Academic fertility center. Patients: Women who became pregnant through in vitro fertilization (IVF) between January 2012-October 2016. Exclusion criteria were: oocyte donation, gestational carrier, multiple gestation, miscarriage before 20 weeks, medically indicated preterm deliverie...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
In this study, we aimed to investigate serum and follicular fluid (FF) secreted frizzle-related protein-5 (Sfrp-5) levels in nonobese, nonhyperandrogenic patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF), in addition to IVF outcomes. In total, 160 patients undergoing IVF treatment were included in the study: 80 patients diagnosed with PCOS according to the Rotterdam criteria (group I, study) and 80 patients with the etiology of male factor infertility (group II, control). There were statistically significant between-group differences in serum estradiol (E2) levels on the day of hCG admi...
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
ConclusionsIn this large cohort of women with PCOS, there was no significant difference in clinical pregnancy rate between women who had tubal patency confirmed by HSG versus SIS. SIS is an acceptable imaging modality for assessment of tubal patency in this population.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
One of the commonest questions which patients ask me is - What ispolycystic ovariandisease (or PCO, also known as PCOD and PCOS? ) And what are its risks ?This has now become a very common diagnosis, and is made by gynecologists, dietitians, skin specialists and GPs as well. The diagnosis is made typically for young girls, who are worried because they irregular periods; are a little bit overweight; or have acne or some oily skin. Doctors order a panel of expensive blood tests ( which measure hormones levels such as FSH, LH, DHEA, testosterone and AMH), and these often turn out to be abnormal in these girls.The problem...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Polycystic ovarian syndrome (PCOS) is a relatively common condition associated with infertility, but most women can be treated successfully to achieve pregnancy. This analysis examined the prevalence of PCOS in women seeking to conceive naturally.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
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