Proinflammatory Cytokines, Enolase and S-100 as Early Biochemical Indicators of Hypoxic-Ischemic Encephalopathy Following Perinatal Asphyxia in Newborns

Estimation of the neurological prognosis of infants suffering from perinatal asphyxia and signs of hypoxic-ischemic encephalopathy is of great clinical importance; however, it remains difficult to satisfactorily assess these signs with current standard medical practices. Prognoses are typically based on data obtained from clinical examinations and neurological tests, such as electroencephalography (EEG) and neuroimaging, but their sensitivities and specificities are far from optimal, and they do not always reliably predict future neurological sequelae.

Source: Pediatrics and Neonatology - August 9, 2016 Category: Perinatology & Neonatology Authors: Ver ónica Chaparro-Huerta, Mario Eduardo Flores-Soto, Mario Ernesto Merin Sigala, Juan Carlos Barrera de León, María de Lourdes Lemus-Varela, Blanca Miriam de Guadalupe Torres-Mendoza, Carlos Beas-Zárate Tags: Original article Source Type: research