How immune response differs for natural AAV infection compared to AAV vector for gene transfer?
(Mary Ann Liebert, Inc./Genetic Engineering News) A new, long-term study examined the antibody response to natural infection with adeno-associated virus in chimpanzees for the purpose of characterizing the broad-based immune responses that could reduce the effectiveness of AAV vector-based gene delivery strategies. The study, which demonstrated the production of antibodies able to cross-neutralize multiple AAV serotypes, is published in Human Gene Therapy Clinical Development.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news
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