Endocardial radiofrequency septal ablation — A new option for non-surgical septal reduction in patients with hypertrophic obstructive cardiomyopathy (HOCM)?: A systematic review of clinical studies

LVOT obstruction has multiple deleterious physiological effects including reduction of forward cardiac output, mitral regurgitation of varying degrees, load dependent diastolic dysfunction leading to an increase in LV end-diastolic pressure and coronary flow abnormalities. These factors contribute to symptoms of dyspnoea, chest pain, pre-syncope, and syncope. LVOT obstruction is associated with a greater level of morbidity and mortality within a population of HCM patients and now forms part of accepted risk stratification models for sudden cardiac death in HCM.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Correspondence Source Type: research