Endoluminal application of glass ‐capped diffuser for ex vivo endovenous photocoagulation

Endovenous laser ablation (EVLA) has frequently been used to treat varicose veins for 20 years. In spite of 90˜95% occlusion rates, clinical complications such as burn and ecchymosis still occur due to excessive thermal injury to perivenous tissue. In the current study, a glass‐capped diffusing applicator is designed to validate the feasibility of EVLA as an effective therapeutic device by applying circumferential light distribution. The proposed device is evaluated with a flat fiber as a reference in terms of temperature elevation, fiber degradation, and degree of coagulative necrosis after 532 nm‐assisted EVLA at 100 J/cm. The diffusing fiber generates a 40% lower maximum temperature with a 90% lower transient temperature change in blood, compared to the flat fiber. Due to low irradiance (13.5 kW/cm2) and wide light distribution, the diffuser tip experiences no significant thermal degradation while severe carbonization occurs at the flat fiber tip. Ex vivo tissue tests verify that the diffusing fiber induces circumferential and consistent tissue denaturation to the vein wall (107.8 ± 7.8 µm) along with 19% vessel shrinkage. The proposed glass‐capped diffusing applicator can be a feasible therapeutic device for EVLA with minimal complications by entailing low maximum temperatures and uniform tissue denaturation in the venous tissue. Endovenous laser ablation (EVLA) is a minimally invasive method to thermally treat varicose veins. This pap...
Source: Journal of Biophotonics - Category: Physics Authors: Tags: Full Article Source Type: research

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CONCLUSION: Using propensity score-matched analysis we showed that pharmacological thromboprophylaxis after EVLA seems to be equally effective with 3 days or 10 days of treatment with a similar success rate and safety profile. Undoubtedly, a large randomised control trial, ideally including a group without pharmacological thromboprophylaxis, is needed to draw more definitive conclusions on the optimal duration of pharmacological post-EVLA thromboprophylaxis. PMID: 31869428 [PubMed - in process]
Source: Swiss Medical Weekly - Category: General Medicine Authors: Tags: Swiss Med Wkly Source Type: research
CONCLUSION: EVLA and RF therapies in saphenous vein insufficiency are effective, minimally invasive, safe, easy to use treatment modalities with good patient satisfaction and high occlusion rates. KEY WORDS: EVLA, Radiofrquency, Venousinsufficiency. PMID: 31661439 [PubMed - as supplied by publisher]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
By Crabby McSlacker What exactly is a Pono Board? Do you surf on it? Fling it? Predict the future by letting ancient Hawaiian spirits telepathically move aqua-colored balls around on its sleek wooden surface until your destiny is revealed?Nope, it's none of these things. A Pono Board is a kinder, gentlerbalance board that can be used to add a bit of instability to various exercises in a way that is mercifully unlikely to send you sprawling on your face in an ignominious heap of kluzitude.Ta da!According to The Pono People, it was designed to feel like a beach workout, actively engaging the core, but not too difficult.But t...
Source: Cranky Fitness - Category: Consumer Health News Authors: Source Type: blogs
Conclusions The NBCA-based vein sealing system is a fast and effective treatment option for the management of incompetent saphenous veins that does not involve tumescent anesthesia, compression stockings, paresthesia, burn marks, or pigmentation. Further large-scale studies with long-term outcomes are required to identify the optimal treatment modalities for patients with saphenous vein insufficiency.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
SPECIAL FROM Varicose veins, a vascular disease that causes swollen, twisted veins, affect up to 35 percent of the American population. They are usually found in the legs, but can appear elsewhere on the body. Also known as venous insufficiency, varicose veins occur when damaged veins have trouble sending blood from the legs to the heart. There are a lot of myths out there about this condition. We talked to Kathleen Gibson, MD, vascular surgeon and vein specialist of Lake Washington Vascular, Bellevue, WA, to get the real deal: Myth #1: Varicose veins are harmless. Dr. Gibson: Varicose veins can be just a cosmetic iss...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
It made sense at the time. If sitting for hours a day is linked to obesity, heart disease and early death, then surely standing or walking while working could help office-goers protect themselves from these health maladies. But a new analysis found that it’s still unclear whether standing or treadmill desks have any positive effect at all on health. What's more, it’s not even clear whether having these new kinds of desks significantly reduces the amount of time a person sits during the work day. The analysis of 20 previous studies -- together including a total of 2,174 participants -- was co...
Source: Science - The Huffington Post - Category: Science Source Type: news
The objective of the present guidelines is to properly guide the diagnosis and treatment of lower leg ulcers/varicose veins by systematically presenting evidence‐based recommendations that support clinical decisions.
Source: The Journal of Dermatology - Category: Dermatology Authors: Tags: Guideline Source Type: research
CONCLUSION: All patients achieved good or excellent improvement after EVLP-1064nm and EVLP-810nm. However, the difference of final outcome was significant, and indicates that improvement was greater in the Diode group. Further studies of different wavelengths and optimization of cryogen spray cooling (CSC) may lead to improved results in the eradication of varicose veins. PMID: 24511201 [PubMed]
Source: Laser Therapy - Category: Laser Surgery Tags: Laser Ther Source Type: research
The objective of the MAS evidence review was to conduct a systematic review of the available evidence on the safety, effectiveness, durability and cost-effectiveness of endovascular laser therapy (ELT) for the treatment of primary symptomatic varicose veins (VV). BACKGROUND: The Ontario Health Technology Advisory Committee (OHTAC) met on November 27, 2009 to review the safety, effectiveness, durability and cost-effectiveness of ELT for the treatment of primary VV based on an evidence-based review by the Medical Advisory Secretariat (MAS). CLINICAL CONDITION: VV are tortuous, twisted, or elongated veins. This can be due...
Source: Ontario Health Technology Assessment Series - Category: Journals (General) Tags: Ont Health Technol Assess Ser Source Type: research
Conclusion Endovenous laser ablation for GSV reflux is a safe, feasible and efficient outpatient technique.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research
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