Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in South America.

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in South America. J Med Microbiol. 2016 Aug 5; Authors: Rodriguez CH, Balderrama Yarhui N, Nastro M, Nuñez Quezada T, Castro Cañarte G, Magne Ventura R, Ugarte Cuba T, Valenzuela N, Roach F, Mota MI, Burger N, Velázquez Aguayo G, Ortellado-Canese J, Bruni G, Pandolfo C, Bastyas N, Famiglietti A Abstract One hundred and twenty-six sequential, epidemiologically unrelated carbapenem-resistant- Acinetobacter baumannii isolates from 9 hospitals of 6 countries of South America were collected between July 2013 and June 2014. Genes coding for Ambler class D and B carbapenemases were sought by PCR. All isolates were typed using the 3-locus sequence typing and blaOXA-51-like sequence based typing techniques. The blaOXA-23 gene was recovered in all the participating hospitals and in all the isolates of 7/9 medical centers. The blaOXA-72 gene was only recovered in the two medical centers from Guayaquil city, Ecuador. Trilocus sequence typing revealed the presence of SG 2, 4 and 5. blaOXA-51-like sequence based typing revealed the presence of blaOXA-132, blaOXA-65, blaOXA-69 and blaOXA-64. Our results showed that the population of carbapenem-resistant- A. baumannii in South America was principally associated with ST79, ST25 and ST15 (92%) and harbored the blaOXA-23 gene, mainly. CC2 was not detected. PMID: 27498975 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research