Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

Conclusions Taken together, our data of animal experiments suggest that increased blood ethanol levels in patients with NAFLD may result from insulin-dependent impairments of ADH activity in liver tissue rather than from an increased endogenous ethanol synthesis. Trial registration number NCT01306396.

http://gut.bmj.com/cgi/content/short/65/9/1564?rss=1

Source: Gut - August 8, 2016 Category: Gastroenterology Authors: Engstler, A. J., Aumiller, T., Degen, C., Dürr, M., Weiss, E., Maier, I. B., Schattenberg, J. M., Jin, C. J., Sellmann, C., Bergheim, I. Tags: Nonalcoholic steatosis Hepatology Source Type: research