The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/{beta}-catenin signalling pathway

Conclusions
We identified PRC1 as a novel Wnt target that functions in a positive feedback loop that reinforces Wnt signalling to promote early HCC recurrence.

Source: Gut - August 8, 2016 Category: Gastroenterology Authors: Chen, J., Rajasekaran, M., Xia, H., Zhang, X., Kong, S. N., Sekar, K., Seshachalam, V. P., Deivasigamani, A., Goh, B. K. P., Ooi, L. L., Hong, W., Hui, K. M. Tags: Open access, Colon cancer, Hepatic cancer Hepatology Source Type: research