Circulating levels of soluble low-density lipoprotein receptor-related protein 1 (sLRP1) as novel biomarker of epicardial adipose tissue
Epicardial adipose tissue (EAT) is not only a lipid storage organ but also a metabolic active and endocrine organ that secrete a number of inflammatory and endocrine mediators [1]. Under normal physiological conditions, EAT exerts cardioprotective actions [2], but under pathophysiological circumstances, such as metabolic syndrome or obesity, EAT has been associated with cardiometabolic disease [3]. Indeed, EAT thickness and/or volume has been directly associated with diabetes, hypertension, atrial fibrillation, heart failure and coronary artery disease [3,4].
Source: International Journal of Cardiology - Category: Cardiology Authors: D. de Gonzalo-Calvo, D. Vilades, L. Nasarre, F. Carreras, R. Leta, X. Garcia-Moll, V. Llorente-Cortes Source Type: research
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